The Institute Colloquium: Through the looking glass reimagining the natural protein
Date:
Monday, April 8, 2013 16:30 - 17:30
Speaker:
Stephen Kent (The University of Chicago)
Location:
Raiffeisen Lecture Hall, Central Building
Series:
Institute colloquium
Contact:
Trappl Marie
One of the most intriguing aspects of the biological world is that all protein molecules found in nature are homochiral that is, they are Lproteins, made up exclusively of L-amino acids and the achiral amino acid glycine. My presentation will focus on the preparation and properties of mirror image D-protein molecules not found in nature. I will discuss the use of racemic crystallography for protein structure determination by Xray crystallography. I will also discuss our current research on the systematic development of D-proteins a candidate human therapeutics.