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CALSCALE:GREGORIAN
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TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20260329T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
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BEGIN:STANDARD
DTSTART:20261025T020000
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TZOFFSETTO:+0100
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10
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BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1782201600@ist.ac.at
DTSTART:20260623T100000
DTEND:20260623T110000
DESCRIPTION:Speaker: Lea Becker\nhosted by Robert Seiringer\nAbstract: Char
 acterizing protein dynamics at the atomic level is essential for our under
 standing of biological mechanisms. Whether it is to facilitate metabolite 
 transport\, catalyze reactions\, transmit signals\, or regulate metabolism
  – proteins are constantly in motion and sample multiple conformational 
 states to fulfill their function. Nuclear magnetic resonance (NMR) spectro
 scopy is particularly well suited to elucidate the dynamics of biomolecule
 s on their complex free-energy landscape. In particular\, solid-state magi
 c-angle spinning (MAS) NMR enables the study of large molecular assemblies
 \, protein crystals\, or insoluble proteins at atomic resolution without a
 n inherent molecular size limitation. MAS NMR experiments to probe protein
  dynamics are extremely versatile and sensitive to motional timescales fro
 m picoseconds to seconds. Over the past decades\, technological advances\,
  developments in experimental design\, and new isotope-labeling approaches
  have further expanded the possibilities of this technique and significant
 ly improved the accuracy of the determined motional parameters.Functionall
 y important sites of proteins often contain aromatic residues. Their side-
 chain motions have therefore long served as valuable indicators of mechani
 stically relevant dynamics in NMR studies. In this thesis\, site-specifica
 lly labeled aromatic residues act as sensitive reporters for MAS NMR studi
 es of protein dynamics. The first part addresses how different environment
 s impact side-chain motion by probing ring flips of phenylalanines and tyr
 osines in crystalline proteins and amyloid fibrils. It provides important 
 insights for the analysis of dynamics obtained in non-native protein envir
 onments and emphasizes the complex factors that determine the timescale of
  internal dynamics. In the second part\, the focus shifts towards methodol
 ogical questions regarding the investigation of protein dynamics by 19F MA
 S NMR. The fluorine nucleus exhibits promising characteristics for NMR stu
 dies but also presents significant challenges\, which is why the full meth
 odological potential of 19F MAS NMR has not been fully realized yet. This 
 work demonstrates that paramagnetic doping can considerably reduce the mea
 surement time and improve the sensitivity of fluorinated samples. Finally\
 , 19F MAS NMR is evaluated as a tool for studying protein side-chain dynam
 ics on the example of tryptophans. The results illustrate the challenges i
 n analyzing such experiments and lay the foundation for further developmen
 t of 19F MAS NMR relaxation studies.Taken together\, this thesis highlight
 s the potential of combining specific isotope labeling\, MAS NMR\, and com
 plementary methods such as crystallography and computational simulations t
 o elucidate internal protein dynamics. The further development of such int
 egrative approaches will be crucial to improving our understanding of comp
 lex mechanisms and protein function.
LOCATION:Central Bldg / O1 / Mondi 2a (I01.O1.008)\, ISTA
ORGANIZER:
SUMMARY:Lea Becker: Thesis Defense: Exploring protein dynamics using specif
 ic labeling approaches for solid-state MAS NMR
URL:https://talks-calendar.ista.ac.at/events/6447
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a1e9cbf6f336379210386@ist.ac.at
DTSTART:20260623T161500
DTEND:20260623T171500
DESCRIPTION:Speaker: Filippo Quattrocchi\nhosted by Jan Maas\nAbstract: Man
 y evolutionary PDEs\, both linear and nonlinear (e.g.\, the heat and porou
 s medium equations)\, can be seen as gradient flows in the Wasserstein met
 ric space of probability measures. This classical result provides general 
 tools for existence\, numerical approximation\, uniqueness\, and convergen
 ce estimates under weak assumptions. In this talk\, we extend this perspec
 tive to dynamics driven by an interplay of conservative and dissipative ef
 fects.Our main result is the interpretation of the nonlinear kinetic Fokke
 r-Planck equation as a gradient flow of the free energy in a suitable spac
 e of measures. The geometry of this space is physically motivated\, induce
 d by discrepancies that measure the minimal force needed to steer one conf
 iguration into another. As a consequence\, we obtain approximations of sol
 utions via an implicit Euler scheme.This talk is based on arXiv:2502.15665
 \, in collaboration with G. Brigati (ISTA) and J. Maas (ISTA)\, and ongoin
 g work with G. Brigati (ISTA)\, G. Carlier (CEREMADE\, Paris Dauphine-PSL)
 \, and J. Dolbeault (CEREMADE\, Paris Dauphine-PSL).
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:boosthui@ist.ac.at
SUMMARY:Filippo Quattrocchi: Nonlinear kinetic equations as gradient flows
URL:https://talks-calendar.ista.ac.at/events/6520
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a358154ee7fd120793416@ist.ac.at
DTSTART:20260625T113000
DTEND:20260625T123000
DESCRIPTION:Speaker: Aurora Rossi\nAbstract: This talk introduces Temporal 
 Graph Neural Networks (TGNNs) as models for learning from systems that com
 bine relational structure and temporal dynamics. Starting from basic neura
 l network concepts\, we build up to graph neural networks\, message passin
 g\, and temporal graph settings\, distinguishing between static graphs wit
 h time-varying features and fully evolving graph structures. Through examp
 les in synthetic forecasting\, traffic prediction\, and brain activity mod
 eling\, the tutorial illustrates when graph information can improve tempor
 al learning and how TGNNs capture spatio-temporal dependencies in real-wor
 ld networks.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:joanders@ist.ac.at
SUMMARY:Aurora Rossi: TCS Seminar - An Introduction to Temporal Graph Neura
 l Networks
URL:https://talks-calendar.ista.ac.at/events/6528
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1782720000@ist.ac.at
DTSTART:20260629T100000
DTEND:20260629T110000
DESCRIPTION:Speaker: Jakub Löwit\nhosted by Krishnendu Chatterjee\nAbstrac
 t: We develop and employ techniques from equivariant algebraic K-theory an
 d related invariants in the context of geometric representation theory\, i
 n both arithmetic and topological situations. We showcase the use of such 
 techniques on the affine Grassmannian Gr\, a space of fundamental interest
  in the geometric Langlands program.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 ) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Jakub Löwit: Thesis Defense: Equivariant K-theory of affine Grassm
 annians in representation theory and arithmetic
URL:https://talks-calendar.ista.ac.at/events/6500
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1782725400@ist.ac.at
DTSTART:20260629T113000
DTEND:20260629T123000
DESCRIPTION:Speaker: Julia Reisenbauer & Charles Roques-Carmes\nhosted by J
 ohannes Fink & Latha Venkataraman\nAbstract: Scaling Light\, Integrating M
 atter\, Imaging the NanoscaleModern photonic technologies increasingly rel
 y on the ability to control\, manipulate\, and process light within compac
 t and scalable integrated platforms. At the same time\, advances in functi
 onal and quantum materials are expanding the range of optical phenomena th
 at can be engineered on chip\, enabling new approaches to light generation
 \, detection\, nonlinear interactions\, and radiation sensing. As photonic
  circuits grow from a few elements to hundreds or thousands of reconfigura
 ble degrees of freedom\, they open new opportunities in imaging\, sensing\
 , computing\, and quantum technologies.In this talk\, I will describe how 
 my group at ISTA aims to build next-generation optoelectronic platforms by
  combining scalable photonics\, functional materials\, and advanced charac
 terization. I will first discuss programmable integrated photonic systems 
 that manipulate partially coherent light on chip\, enabling new measuremen
 t modalities that would be difficult to realize in free space. I will then
  turn to the integration of emerging materials into nanophotonic devices\,
  with a focus on radiation-sensitive materials that can reshape how X-rays
  are converted into optical information. These platforms point toward nano
 photonic scintillators\, metasurface-enhanced radiation detectors\, and qu
 antum-optical approaches to high-energy imaging.Finally\, I will discuss t
 he microscopy tools we are developing to characterize these increasingly c
 omplex nanophotonic and nanomaterial systems. More broadly\, our goal is t
 o establish integrated photonics as a scalable physical platform for revea
 ling\, controlling\, and exploiting light-matter interactions across optic
 al\, quantum\, and high-energy regimes._______Reprogramming Enzymes to Cat
 alyze Non-native ReactionsEnzymes are Nature’s catalysts\, evolved to co
 nstruct and degrade molecules with remarkable efficiency and selectivity. 
 Although their activities have been shaped by natural selection to fulfill
  specific biological functions\, many enzymes retain promiscuous catalytic
  activities toward non-native substrates and reactions. By leveraging fund
 amental concepts such as catalytic promiscuity and directed evolution\, we
  repurpose and engineer these enzymes for applications in synthetic chemis
 try and bioremediation\, enabling the degradation of emerging environmenta
 l contaminants while simultaneously expanding the accessible chemical spac
 e and introducing new reactions to the synthetic chemist’s toolkit.
LOCATION:ISTA | Central Building | Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Julia Reisenbauer & Charles Roques-Carmes: Scaling Light\, Integrat
 ing Matter\, Imaging the Nanoscale & Reprogramming Enzymes to Catalyze Non
 -native Reactions
URL:https://talks-calendar.ista.ac.at/events/6385
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a313b62abbad282106005@ist.ac.at
DTSTART:20260629T140000
DTEND:20260629T150000
DESCRIPTION:Speaker: Morgan Chabanon\nhosted by Jérémie Palacci\nAbstract
 : Transport phenomena in biological systems are essential for life-sustain
 ing functions. Here we propose to approach biological materials such as ti
 ssues\, biofilms and cells as porous media.We will first focus on the pass
 ive transport of macromolecules in the intracellular space\, involved in f
 unctions such as cell migration\, blebbing and apoptosis. While intracellu
 lar crowding significantly impacts macromolecule mobility\, the mechanisms
  by which cytoplasmic structures influence diffusion remain unclear. We pr
 opose a multiscale diffusion model based on an upscaling method developed 
 for porous media. Model predictions\, compared to experimental measurement
 s in live cells\, highlight two key diffusion reduction mechanisms: tortuo
 sity and hydrodynamic drag. Importantly\, we find that effective cytosolic
  diffusivity depends on intracellular obstacle volume fraction rather than
  specific cellular regions.We will then consider suspensions of motile bac
 teria in porous media\, relevant for soil bioremediation and biomedical ap
 plications. In confined environments at high cell density\, these suspensi
 ons behave as active fluids displaying self-sustained coherent or chaotic 
 flows. We use a continuum framework derived from FokkerPlanck descriptions
  to predict emerging flows in channels with different pore geometries as a
  function of activity and pressure gradient. Numerical results show a devi
 ation from Darcy law\, which we relate to an activity enhanced permeabilit
 y.Altogether\, these results demonstrate the potential of porous media mod
 eling to better understand transport phenomena in living matter across sca
 les and systems.
LOCATION:Moonstone Bldg / Ground floor / Seminar Room F (I24.EG.030f)\, IST
 A
ORGANIZER:cpetz@ist.ac.at
SUMMARY:Morgan Chabanon: Transport in porous media modelling of intracellul
 ar diffusion and active bacteria suspensions
URL:https://talks-calendar.ista.ac.at/events/6524
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a228b5ab4e49352705797@ist.ac.at
DTSTART:20260630T161500
DTEND:20260630T171500
DESCRIPTION:Speaker: Reuben Drogin\nhosted by Laszlo Erdös\nAbstract: The 
 FurstenbergKesten theorem asserts that the singular values of a product of
  IID random matrices grow or decay exponentially at deterministic rates\, 
 called Lyapunov exponents. Classical results give qualitative criteria ens
 uring that these exponents are distinct and or positive\, but many applica
 tions\, e.g. the theory of random band matrices\, require quantitative est
 imates. We discuss such estimates and their connections to localization fo
 r random band matrices. In particular\, we show the Lyapunov exponents ass
 ociated with a class of 2W x 2W transfer matrices are separated at scale 1
 /W\, and the top Lyapunov exponent converges to a deterministic limit as W
  tends to infinity.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:boosthui@ist.ac.at
SUMMARY:Reuben Drogin: Singular Values of Random Matrix Products and Random
  Band Matrices
URL:https://talks-calendar.ista.ac.at/events/6501
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a1e9cbf6f7a1927120699@ist.ac.at
DTSTART:20260630T171500
DTEND:20260630T181500
DESCRIPTION:Speaker: Francesco Pedrotti\nhosted by Jan Maas\nAbstract: The 
 cutoff phenomenon is a sharp transition in the convergence of high-dimensi
 onal Markov chains to equilibrium: the total variation distance remains cl
 ose to 1 for a long time and then rapidly decreases to almost 0 over a muc
 h shorter time window.It was initially discovered in the context of card s
 huffling by Diaconis and Shahshahani\, and since then observed in a variet
 y of different models. In spite of its ubiquity\, it is still largely unex
 plained\, and most proofs are model-specific.In this talk\, we discuss a h
 igh-level approach to establishing cutoff based on transport inequalities\
 , and we illustrate it for a popular algorithm known as the Proximal Sampl
 er.Based on joint work with Justin Salez.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:boosthui@ist.ac.at
SUMMARY:Francesco Pedrotti: A transport approach to the cutoff phenomenon
URL:https://talks-calendar.ista.ac.at/events/6502
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1782918000@ist.ac.at
DTSTART:20260701T170000
DTEND:20260701T180000
DESCRIPTION:Speaker: Simone Bombari\nhosted by Matthew Kwan\nAbstract: Arti
 ficial intelligence and machine learning have undergone an unprecedented e
 volution in the past decade\, motivating a research effort toward a theory
  able to capture the qualitative behavior of large-scale neural systems. A
  central puzzle has been the clear benefit of scaling architecture size an
 d overfitting the training set in supervised learning tasks. This evidence
 \, in apparent contradiction with classical statistical learning theory\, 
 pushed researchers to develop a new theory capturing the interplay between
  the algorithmic and architectural bias of training and the specific targe
 t function\, differently from previous methods rooted in uniform stability
 .This approach has enabled a grounded understanding of novel learning regi
 mes\, typically through formal limits where the number of training samples
  $n$\, data dimensions $d$\, and model parameters $p$ grow to infinity at 
 different rates.In this thesis\, we follow this approach\, focusing on the
  trustworthiness of high-dimensional models: properties that are difficult
  to control during training or deployment and often emerge under unpredict
 able or adversarial conditions. In such settings\, it is crucial to formal
 ly ensure a priori the reliability of machine learning systems.First\, we 
 study data memorization\, both as label fitting and as the storage of priv
 ate information about training samples in trained parameters. We prove tha
 t $p = \\Omega(n)$ parameters are sufficient for a deep neural network to 
 memorize a generic set of labels\, and for a model to memorize spurious fe
 atures across training data. We then give evidence that $p = \\Omega(dn)$ 
 parameters are instead necessary for an adversary to reconstruct the full 
 training set from the trained parameters.Second\, we study robustness\, bo
 th to adversarial perturbations and to distribution shift. We first prove 
 that $p = \\Omega(dn)$ parameters can be sufficient for a class of neural 
 networks to overfit the training data while guaranteeing robustness to adv
 ersarial perturbations. Then\, we focus on spurious correlations learning 
 in high-dimensional regression\, studying the effect of the ridge regulari
 zation parameter in the proportional regime $n = \\Theta(d)$\, and connect
 ing it via an equivalence argument to the role of over-parameterization $p
  = \\Omega(n)$ in neural networks. We also investigate the architectural b
 ias of attention-based networks\, showing that they are sensitive to the r
 eplacement of individual words in an embedded sentence\, allowing them to 
 generalize on sentences where the contextual meaning depends on one or few
  words.Finally\, we study differentially private optimization in high-dime
 nsional regimes. We prove that standard private gradient methods do not su
 ffer in the over-parameterized regime $p = \\Omega(n)$\, challenging the c
 urrent wisdom based on stability-derived generalization bounds. We then co
 nsider linear regression in the proportional regime $n = \\Theta(d)$\, sho
 wing that standard private gradient descent can achieve optimal rates unde
 r appropriate hyper-parameter scaling\, such as sufficiently small gradien
 t clipping constants\, whose role is still debated in practice.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 ) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Simone Bombari: Thesis Defense: Trustworthy Machine Learning in Hig
 h Dimensions
URL:https://talks-calendar.ista.ac.at/events/6499
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1783004400@ist.ac.at
DTSTART:20260702T170000
DTEND:20260702T180000
DESCRIPTION:Speaker: Ignacio Cirac\nhosted by Julian Léonard & Maksym Serb
 yn\nAbstract: Advancements in quantum computing have enabled the developme
 nt of small-scale quantum computers that operate according to the principl
 es of quantum physics. One of the most important prospective applications 
 of these devices is the simulation of complex quantum systems\, which aris
 e across many areas of physics and chemistry. Such simulations are notorio
 usly difficult\, if not impossible\, for classical computers\, even the mo
 st powerful supercomputers\, due to the exponential growth of required com
 putational resources with the number of particles in the system. In this 
 talk\, I will first show how both analog and digital quantum devices could
  circumvent this limitation. Despite rapid progress\, however\, applicatio
 ns in this area remain limited\, as current quantum devices are imperfect:
  errors accumulate and pose serious challenges for solving practically rel
 evant problems. I will discuss how\, even in the presence of such errors\,
  near-term quantum computers can already become powerful tools for scienti
 fic discovery.A reception with food and drinks will be available for all r
 egistered guest after the lecture\, free of charge.Register here (https://
 assets-eur.mkt.dynamics.com/c4c27152-17ec-47dc-b101-24b7ac15e0e6/digitalas
 sets/standaloneforms/432e0451-b7fa-4f34-bdbe-bd16d6a34eab?readableEventId=
 New_event_7110658852) Climate-friendly arrival & departureA shuttle bus w
 ill be available from Heiligenstadt at 14:57 - 15:57The regular shuttle bu
 s will return to Heiligenstadt at 18:28 - 18:58 - 19:28 - 20:28The s
 huttle bus is free of charge for all registered guests.How to get to ISTA 
 Campus (https://ist.ac.at/en/campus/how-to-get-here/#msdynttrid=H5PQdGhs-B
 twLvoi1_nrHlgBiWNIt8n5CeLi0Mv1Y_4) The aim is to organize the event in ac
 cordance with the criteria of the Austrian Ecolabel for Green Meetings (ht
 tps://www.umweltzeichen.at/de/green-meetings-und-events/home). If you have
  any questions about the event's sustainability standards\, please contact
  the Green Event Officer Julia Kainrath (julia.kainrath@ista.ac.at).
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:events@ista.ac.at
SUMMARY:Ignacio Cirac: ISTA Lecture | Ignacio Cirac
URL:https://talks-calendar.ista.ac.at/events/6496
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1783076400@ist.ac.at
DTSTART:20260703T130000
DTEND:20260703T140000
DESCRIPTION:Speaker: Xin Tong\nhosted by Carl Goodrich\nAbstract: Embryo cl
 eavage — a series of rapid\, reductive cell divisions — is the first m
 orphogenetic movement following fertilisation. It lays the foundation for 
 subsequent developmental events\, including gastrulation\, germ layer spec
 ification\, organogenesis\, and the establishment of the overall body plan
 . Two major modes of cleavage exist in the animal kingdom: holoblastic (co
 mplete) and meroblastic (incomplete) cleavage. Because holoblastic cleavag
 e resembles canonical cytokinesis\, its biochemical and mechanical basis h
 as been extensively studied — an annular contractile ring forms at the e
 quator and constricts in a purse-string-like manner\, leading to the compl
 ete separation of two daughter cells. In contrast\, although meroblastic c
 leavage occurs widely across the animal kingdom (e.g. in fish\, reptiles\,
  birds\, and cephalopod molluscs)\, its mechanical basis remains largely u
 nclear. During meroblastic cleavage\, the cytokinetic furrow forms only at
  one pole and does not traverse the entire embryo\, raising the question o
 f how cytokinesis proceeds in the absence of a closed contractile ring. Mo
 reover\, the resulting daughter cells are not fully separated from the und
 erlying yolk compartment\, and how these blastomeres are subsequently cell
 ularised remains unknown. This thesis takes the zebrafish as a model organ
 ism to address both questions. The first part characterises the biochemica
 l and mechanical mechanisms underlying non-canonical meroblastic cleavage\
 , revealing a two-phase process in which actomyosin cable contraction and 
 cadherin-mediated membrane adhesion act sequentially to drive furrow ingre
 ssion and invagination. The second part sheds light on the spatiotemporal 
 dynamics by which individual blastomeres become cellularised\, and uncover
 s a previously unrecognised contribution of central blastomeres to the yol
 k syncytial layer.
LOCATION:Central Bldg / O1 / Mondi 3 (I01.O1.010) \, ISTA
ORGANIZER:
SUMMARY:Xin Tong: Thesis Defense: Towards a deeper understanding of merobla
 stic cleavage - biochemical mechanisms of partial cytokinesis and cellular
 ization in zebrafish embryogenesis
URL:https://talks-calendar.ista.ac.at/events/6519
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1783495380@ist.ac.at
DTSTART:20260708T092300
DTEND:20260708T092300
DESCRIPTION:
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Special Colloquium | Presentation of AURAS Survey Results
URL:https://talks-calendar.ista.ac.at/events/6549
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1783598400@ist.ac.at
DTSTART:20260709T140000
DTEND:20260709T150000
DESCRIPTION:Speaker: David Michalik\nhosted by Eva Benková\nAbstract: MDA5
  is an antiviral protein that is activated by long dsRNA molecules. This R
 NA can be of various origins such as viral\, bacterial\, synthetic or\, up
 on certain stimuli\, even cellularsources. Upon sensing immunogenic RNA\, 
 MDA5 coats the dsRNA\, forming a filament. Filament formation brings CARD 
 domains into close proximity\, resulting in CARD oligomerisation. These ol
 igomers are not involved in the RNA recognition but are crucial for activa
 tion of downstream signalling. MDA5 activation leads to a type I interfero
 n response and apoptosis. Loss of function mutations are linked to recurre
 nt\, life-threatening viral infections whereas gain of function mutations 
 are linked to monogenic and polygenic autoimmune diseases. For these reaso
 ns\, MDA5 needs to be tightly regulated by various mechanisms including po
 st-translational modifications\, post-transcriptional modifications\, and 
 protein-protein interactions. In the first chapter\, we focused on the cha
 racterisation of novel phosphorylation sites in MDA5. Using biochemistry\,
  molecular dynamics simulations\, virology\, cell biology and mass spectro
 metry\, we characterised two phosphorylation sites that altered MDA5 activ
 ity andwere regulated in cells upon EMCV infection or IFN-β treatment. Fu
 rthermore\, we discovered an additional phosphorylation site in a non-cons
 erved region\, which is upregulated under both stimuli.In the second chapt
 er\, we focused on biochemical\, biophysical\, and structural characterisa
 tion of various RNAs and MDA5 filaments assembled on them. We discovered t
 hat poly I:C\, a synthetic RNA used to activate an immune response in cell
 s\, has distinct physicochemical characteristics and is not a true mimic o
 f viral RNA\, as is often described. Additionally\, we used cryogenic elec
 tron microscopy to gain structural insights into which RNA features define
  a strong activator of MDA5. To address this\, we compared poly I:C to pol
 y A:U\, an RNA that does not activate an MDA5 signalling in cells\, and to
  a virus-derived dsRNA. In the last chapter\, we focused on activators of 
 MDA5 signalling. In the first part\, we present our efforts to isolate and
  identify a small molecule agonist of MDA5. In the last part\, we describ
 ed our contribution to a collaborative project during which we characteris
 ed the interaction of ANXA2 with MDA5 and activation of MDA5 by a small mo
 lecule.
LOCATION:Office Bldg West / Ground floor / Foyer seminar room (I21.EG.128)\
 , ISTA
ORGANIZER:
SUMMARY:David Michalik: Thesis Defense: Mechanistic insights into MDA5 sele
 ctivity and regulation
URL:https://talks-calendar.ista.ac.at/events/6508
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:67ff786e1151f433679635@ist.ac.at
DTSTART:20260710T150000
DTEND:20260710T160000
DESCRIPTION:Speaker: Ryan J. Murphy\nhosted by Edouard Hannezo\nAbstract: E
 xperiments in biology generate a vast amount of data across multiple spati
 al and temporal scales. However\, interpreting such complex data is challe
 nging. Mechanistic mathematical modelling\, together with statistical mode
 lling\, provides a powerful framework for exploiting such data to achieve 
 mechanistic understanding\, quantitative insights\, and discoveries. In th
 is talk\, I will present novel mathematical models and techniques that I h
 ave developed and applied to improve practical understanding of routinely 
 performed two- and three-dimensional biological experiments for cancer gro
 wth\, nanoparticle-based therapeutics\, and developmental biology. Mathema
 tically\, this involves stochastic individual-based models\, coarse-graini
 ng procedures\, coupled systems of nonlinear partial differential equation
 s\, free-boundary problems\, and multi-scale mechanochemical models that c
 apture key biological heterogeneity.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:kiyer@ist.ac.at
SUMMARY:Ryan J. Murphy: Multiscale modelling of heterogeneous cell-tissue d
 ynamics
URL:https://talks-calendar.ista.ac.at/events/5823
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1784038500@ist.ac.at
DTSTART:20260714T161500
DTEND:20260714T180000
DESCRIPTION:Speaker: Lihan Wang\nhosted by Giovanni Brigati\nAbstract: Abst
 ract: In this talk\, we discuss the long-time behavior of three most comm
 only used piecewise deterministic samplers\, namely Randomized Hamiltonian
  Monte Carlo (RHMC)\, Zigzag process (ZZP) and Bouncy Particle Sampler (BP
 S). All of these\, alongside kinetic Langevin dynamics\, are second-order 
 lifts of the overdamped Langevin dynamics. The kinetic samplers are advant
 ageous due to its potentially accelerated long-time convergence rates and 
 high accuracy in numerical implementation. We discuss the long-time behavi
 or of these samplers\, in both L^2 energy and relative entropy\, and showc
 ase the difference between these dynamics\, as well as the difference betw
 een L^2 energy and entropy\, explaining why the convergence results in ent
 ropy cannot be generalized to entropy. Joint works with Jianfeng Lu (Duke)
  and Pierre Monmarché (U Gustave Eiffel).
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:Birgit.Oosthuizen-Noczil@ist.ac.at
SUMMARY:Lihan Wang: Long-time behavior of piecewise deterministic samplers:
  from energy to entropy\, convergence and non-convergence
URL:https://talks-calendar.ista.ac.at/events/6545
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1784278800@ist.ac.at
DTSTART:20260717T110000
DTEND:20260717T120000
DESCRIPTION:Speaker: Christine Fiedler\nhosted by Edouard Hannezo\nAbstract
 : Thermoelectric materials can directly convert between heat and electrici
 ty\, offering a route toward sustainable energy generation. However\, thei
 r use remains limited to niche applications due to high fabrication costs 
 and relatively low efficiencies compared to competing energy technologies.
  Tin chalcogenides such as SnSe and SnS are promising candidates and\, whe
 n processed via solution-based routes\, provide a scalable and lower-cost 
 alternative to conventional solid-state synthesis\, opening pathways towar
 d broader adoption. However\, realizing their full potential in polycrysta
 lline form requires a deeper understanding of how defects\, dopants\, and 
 microstructure govern charge and heat transport.This thesis demonstrates t
 hat\, in solution-processed materials\, dopants including those introduced
  unintentionally through precursor chemistry\, are not just confined to sp
 ecific lattice sites. Instead\, they distribute across the microstructure\
 , partitioning within grain interiors\, grain boundaries\, and segregated 
 regions\, where they govern grain growth\, carrier concentration\, and cha
 rge transport. Through a systematic study of alkali metals and lead halide
 s in SnSe and SnS\, this work links synthesis\, defect partitioning\, micr
 ostructure evolution\, and thermoelectric performance reshaping how high-p
 erformance p- and n-type thermoelectric materials are designed.
LOCATION:Sunstone Bldg / Ground floor / Big Seminar Room B (I23.EG.102) and
  Zoom\, ISTA
ORGANIZER:
SUMMARY:Christine Fiedler: Thesis Defense: Mechanistic Insight into Solutio
 n-Processed P-type Tin Chalcogenides as a Basis for Designing their N-type
  Analogs
URL:https://talks-calendar.ista.ac.at/events/6530
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1785229200@ist.ac.at
DTSTART:20260728T110000
DTEND:20260728T120000
DESCRIPTION:Speaker: Miguel Cueto Noval\nhosted by Carrie Bernecky\nAbstrac
 t: The widespread adoption of apps like Whatsapp and Signal has translated
  into billions of people all around the world communicating on a regular b
 asis by making use of services that offer end-to-end encryption and even p
 rovide security guarantees when a user's device is compromised.This was ma
 de possible by the introduction of the Double Ratchet Algorithm\, which wa
 s designed for a setting where communication takes place between two parti
 es. However\, in practice\, many apps offer the possibility of creating gr
 oups. The protocols they use to secure communication are inefficient for l
 arge group which has the undesirable consequence that the aforementioned a
 pps have established limits on the group size of roughly 1000 users. This 
 has motivated the introduction of the Messaging Layer Security (MLS) stand
 ard by the IETF which is based on a primitive called Continuous Group Key 
 Agreement (CGKA).This primitive allows a group of users to maintain a shar
 ed secret key that is frequently rotated by the group members in order to 
 change group membership\, achieve forward secrecy (FS) and post compromise
  security (PCS). Most protocols are based on binary trees where the nodes 
 are associated to a pair formed by public key and a secret key. Each leaf 
 corresponds to one of the group members and a user knows the secret keys a
 ssociated to nodes along the path from their leaf to the root. When a user
  wants to update their key material they have to change $ \\log(N) $ many 
 keys. This requires uploading $ \\log(N) $ many ciphertexts to communicate
  the new keys to the rest of the group members in a way that respects the 
 tree structure.In this thesis we study how much communication between grou
 p members is required in order to add and remove users from a group as wel
 l as in order to provide PCS when we consider CGKAs built using standard c
 ryptographic primitives like pseudo-random functions and public-key encryp
 tion. Furthermore\, we also consider the case of MLS and provide the first
  lower bound showing that its communication complexity is much worse than 
 previously believed\, i.e.\, it is very far from $ \\log(N) $. Finally\, w
 e also propose a variant of MLS which provably achieves the same security 
 properties with a much lower communication cost.
LOCATION:Moonstone Bldg / Ground floor / Seminar Room F (I24.EG.030f ) and 
 Zoom\, ISTA
ORGANIZER:
SUMMARY:Miguel Cueto Noval: Thesis Defense: Towards Efficient Secure Group 
 Messaging
URL:https://talks-calendar.ista.ac.at/events/6544
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1785322800@ist.ac.at
DTSTART:20260729T130000
DTEND:20260729T140000
DESCRIPTION:Speaker: Arsenii Solovev\nhosted by Pavol Harar\nAbstract: Dear
  colleagues\, let's talk about cryoEM/ET! Again!Registration: https://luma
 .com/ukgvmyza Intranet: https://intranet.ista.ac.at/content/perma?id=1903
 21 It is our pleasure to invite you to the next CryoCoffee—a casual\, o
 ne-hour meetup (quarterly) for anyone at ISTA interested in cryo-electron 
 microscopy (cryo-EM)\, cryo-electron tomography (cryo-ET)\, or related top
 ics. Whether you work directly with these techniques\, develop computation
 al methods\, tackle inverse problems\, or are simply curious\, this is an 
 opportunity to connect with others\, exchange ideas\, and find potential c
 ollaborations. We will be happy to welcome biologists\, mathematicians\, c
 omputer scientists\, physicists\, chemists\, and basically anyone interest
 ed in cryo. More info in the registration link.The program includes a shor
 t talk followed by a Mini Poster session to share fresh ideas—not finish
 ed projects.This is a perfect opportunity to get early feedback from colle
 agues. Consider signing up for the casual A4 poster\, it is a great ice br
 eaker that sparks fruitful discussions.
LOCATION:Error Bar\, ISTA
ORGANIZER:Pavol.Harar@ista.ac.at
SUMMARY:Arsenii Solovev: 6th CryoCoffee on 29th July 1PM in ErrorBar 
URL:https://talks-calendar.ista.ac.at/events/6557
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1785740400@ist.ac.at
DTSTART:20260803T090000
DTEND:20260807T140000
DESCRIPTION:
LOCATION:Moonstone Seminar Center\, ISTA
ORGANIZER:eurowd-2026@ista.ac.at
SUMMARY:24th European Workshop on White Dwarfs
URL:https://talks-calendar.ista.ac.at/events/6292
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1785744000@ist.ac.at
DTSTART:20260803T100000
DTEND:20260803T110000
DESCRIPTION:Speaker: Felix Pertl\nhosted by Georgios Katsaros\nAbstract: Co
 ntact electrification (CE) is a simple yet elusive phenomenon that occurs 
 when two materials come into contact and separate\, leaving behind net ele
 ctrical charge. Despite its ubiquity\, the microscopic origin of CE remain
 s unclear. In this thesis\, we investigate CE from three complementary per
 spectives: developing a quantitative method to measure charge at the nanos
 cale\, exploring the dynamic behavior of charge on insulating surfaces\, a
 nd uncovering the role of mechanical history in forming a triboelectric se
 ries.In the first part\, we establish a rigorous framework for converting 
 qualitative Kelvin probe force microscopy (KPFM) voltage maps into quantit
 ative charge density distributions. Using finite element method (FEM) simu
 lations\, we determine the point-spread function of the KPFM tip–sample 
 geometry and demonstrate that the true surface charge can be reconstructed
  by numerical deconvolution. This procedure enables the recovery of both t
 he magnitude and sign of charge density with high fidelity\, resolving nan
 oscale features that are otherwise obscured. Applying the method to contac
 t-charged SiO$_2$ surfaces\, we show that existing analytical approximatio
 ns\, such as parallel plate or spherical models\, can miscalculate charge 
 magnitude by orders of magnitude. Our hybrid FEM/KPFM approach therefore p
 rovides a fast and general method to convert qualitative KPFM signals into
  quantitative charge data\, enabling nanoscale charge mapping under realis
 tic experimental conditions.In the second part\, we study the temporal sta
 bility of CE-induced charges and identify the key material factors that de
 termine whether KPFM can capture meaningful charge patterns. Through time-
 resolved experiments combining a custom-built transfer system with both mi
 croscopic and macroscopic measurements\, we demonstrate that only the best
  insulators\, such as SiO$_2$\, preserve CE charge long enough for station
 ary imaging. For less conductive polymers\, such as PDMS\, charge decays w
 ithin the duration of a single KPFM scan due to bulk conduction. Using a s
 imple capacitor-based model\, we reproduce the observed decay dynamics and
  confirm that the transferred charge decays characteristic to the sample's
  bulk conductivity. Further\, we always observe homogeneous charge transfe
 r.In the third part\, we address the question: can we form a triboelectric
  series with identical materials? Using controlled repetitive contact expe
 riments\, we show that nominally identical materials can progressively ord
 er themselves into a triboelectric series\, where surfaces with more conta
 ct history charge negatively relative to fresher ones. By constructing a m
 inimal model based on this contact bias''\, we replicate the evolution fro
 m random to ordered charging observed in experiments. Supporting surface a
 nalyses\, including atomic force microscopy\, reveal that repeated contact
  induces nanoscale morphological changes\, suggesting a mechanism tightly 
 coupled to mechanical strain. These results highlight the crucial role of 
 surface history and nanoscale mechanics in dictating charge transfer\, mot
 ivating further exploration of mechanisms such as mechanochemical bond cle
 avage and flexoelectric polarization.
LOCATION:Sunstone Bldg / Ground floor / Big Seminar Room B (I23.EG.102)\, I
 STA
ORGANIZER:
SUMMARY:Felix Pertl: Thesis Defense: Experimental probing of nanoscale char
 ge features and surface morphology changes during tribocharging
URL:https://talks-calendar.ista.ac.at/events/6537
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1785744000@ist.ac.at
DTSTART:20260803T100000
DTEND:20260803T110000
DESCRIPTION:Speaker: Marek Randuch\nhosted by Michael Sixt\nAbstract: Root 
 growth inhibition (RG) by auxin and other cues (e.g. eATP\, RALF peptide) 
 involves rapid\, non-transcriptional pathways. Specific steps leading to g
 rowth inhibition are unclear. Notably\, the RG inhibition is associated wi
 th increases in cytosolic Ca2+\, plasma membrane depolarization and apopla
 st alkalization. However\, the causal relationship between them is unclear
 . To untangle these processes\, we utilized multiplexed reporter imaging 
 to observe pairwise the real-time dynamics of these three processes. Furth
 ermore\, we tested causal relationships. We employed microfluidics for rap
 id medium exchange and leveraged new optogenetically regulated channels. 
 Our comprehensive approach uncovered a network with tight feedback loops. 
 Results indicate that cytosolic Ca2+ serves as the universal initial signa
 l\, triggering both plasma membrane depolarization and subsequent apoplast
  alkalization following auxin perception. his conclusion provides a basis 
 for the fundamental regulatory mechanism governing growth but also opens q
 uestions about the molecular mechanisms behind it.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 ) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Marek Randuch: Thesis Defense: Fast growth responses in plants: Pho
 spho‐proteomic and growth regulation
URL:https://talks-calendar.ista.ac.at/events/6553
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a621a7000aa7530372093@ist.ac.at
DTSTART:20260805T110000
DTEND:20260805T120000
DESCRIPTION:Speaker: Christina Henzinger\nhosted by Hryhoriy Polshyn\nAbstr
 act: Exchange statistics are a fundamental principle of quantum mechanics\
 , dictating the symmetry of identical particle wavefunctions. The exchange
 -induced unitary transformation of anyonic wavefunctions can be probed usi
 ng electronic fractional quantum Hall (FQH) interferometers\, where quasip
 articles on the interfering FQH edge braid with those localized within the
  cavity. Here\, we add a gate-controlled dot/anti-dot in the center of a b
 ilayer graphene FQH interferometer to tune the number of enclosed anyons. 
 We observe hundreds of controlled phase slips in the conductance across th
 e interferometer for both abelian and non-abelian states\, consistent with
  discrete changes in the localized quasiparticle population. For abelian a
 nyons\, the observed phase slips agree with the theoretically expected val
 ue. At half filling\, our results suggest the interfering edge carries cha
 rge |e/e| = 1/2 abelian excitations\, whereas charge |e/e| = 1/4 putative 
 non-abelian anyons remain localized in the interferometer cavity. Controll
 ing the population of localized e/4 anyons in an interferometer marks a si
 gnificant milestone towards observing their non-local exchange statistics 
 and building a fault tolerant topological qubit based on non-abelian anyon
  manipulation.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:hpolshyn@ist.ac.at
SUMMARY:Christina Henzinger: Controlled localization of anyons in a graphen
 e quantum Hall interferometer
URL:https://talks-calendar.ista.ac.at/events/6571
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1785934800@ist.ac.at
DTSTART:20260805T150000
DTEND:20260805T160000
DESCRIPTION:Speaker: Silvia Jamrichova\nhosted by Maria Ibáñez\nAbstract:
  A fundamental question in neuroscience is how the biophysical properties 
 of synapses shape higher network computations. The mossy fiber synapse is 
 a key synapse of the trisynaptic circuit of the hippocampus\, a brain regi
 on central to the encoding and retrieval of declarative memory. Its unique
  size\, large vesicle pool\, wide range of plasticity\, striking "detonato
 r" properties\, and involvement in several higher-order computations\, nam
 ely pattern separation and pattern completion\, make it an ideal model for
  studying synaptic mechanisms with direct relevance to memory and its impa
 irments.Despite extensive study over the years\, however\, key questions r
 emain unresolved: the molecular identity of the Ca² sensors driving its d
 istinct modes of release and plasticity\, and whether its fundamental prop
 erties are preserved in the human brain.Thanks to newly generated transgen
 ic mice and a method of direct presynaptic patch-clamp recordings from mos
 sy fiber boutons\, we used a combination of electrophysiological\, imaging
  and behavioral methods to investigate the role of synaptotagmins in timin
 g of transmission and plasticity at this synapse.We found that Syt1 is the
  primary Ca² sensor for synchronous release\, with a major trigger and mi
 nor clamping function of neurotransmitter release. Syt1 deletion led to an
  increase in asynchronous release converting the teacher synapse from a te
 mporally precise conditional detonator to an asynchronous one. Moreover\, 
 at the behavioral level\, desynchronized release selectively impaired patt
 ern completion\, while pattern separation remained intact\, demonstrating 
 that disruption of its precise timing and strength leads to selective impa
 irments in behaviorally relevant hippocampal computations in mice. Interes
 tingly\, our data did not support a proposed role for Syt7 in either async
 hronous release\, or facilitation or pool refilling\, leaving its function
  at this synapse enigmatic.Furthermore\, utilizing non-sclerotic tissue ob
 tained from temporal lobe epilepsy patients undergoing brain surgery\, we 
 discovered several notable species differences: human mossy fiber boutons 
 display larger vesicle pools and amplitude responses\, and — strikingly 
 — exhibit full detonator properties in CA3. Furthermore\, mossy fiber sy
 napses targeting CA4 neurons lack such properties\, suggesting a distinct 
 functional role at this projection.Together\, the findings presented in th
 is thesis shed light on the molecular mechanisms underlying information pr
 ocessing at the hippocampal mossy fiber synapse\, with implications for ou
 r understanding of memory\, and reveal both conserved and distinct synapti
 c properties between mice and humans\, suggesting that human mossy fibers 
 are not a simple scaled version of their rodent counterpart.
LOCATION:Central Bldg / O1 / Lecture Hall (I02.O1.014) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Silvia Jamrichova: Thesis Defense: Timing and strength of synaptic 
 transmission at hippocampal mossy fiber synapses in mice and humans
URL:https://talks-calendar.ista.ac.at/events/6570
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1786021200@ist.ac.at
DTSTART:20260806T150000
DTEND:20260806T160000
DESCRIPTION:Speaker: Peipeng Lin\nhosted by Charles Roques-Carmes\nAbstract
 : The hippocampal mossy fiber (MF) to CA3 pyramidal neuron synapse plays a
  key role in hippocampal information processing\, acting as a teacher syna
 pse that can conditionally drive postsynaptic firing and instruct informat
 ion storage in the downstream CA3 network. How the detonation properties o
 f this synapse are kept in check remains unclear. Our study demonstrates t
 hat CA3 stratum lucidum interneurons inhibit MF synaptic transmission via 
 presynaptic GABAB receptors. Pharmacological activation of these receptors
  by baclofen markedly reduced MF synaptic transmission\, switching the syn
 apse from a reliable conditional detonator into a coincidence-detecting su
 bdetonator. We identified a dual mechanism underlying this presynaptic inh
 ibition: a reduction in Ca² influx and\, more substantially\, a decrease 
 in the readily releasable pool of synaptic vesicles. Synaptically released
  GABA\, evoked by optogenetic stimulation of stratum lucidum interneurons 
 at in vivo-like frequencies\, produced comparable effects and further inte
 rfered with the stability of the short-term plasticity-associated vesicle 
 pool engram\, pointing to a physiological role for presynaptic inhibition.
  Expansion microscopy showed that interneuron terminals are positioned in 
 close proximity to MF boutons\, providing a structural basis for GABA spil
 lover onto presynaptic receptors. Together\, our findings reveal how inter
 neuron activity calibrates synaptic efficacy and plasticity at MF synapses
  through presynaptic inhibition\, with implications for memory encoding in
  the hippocampal trisynaptic circuit.
LOCATION:Central Bldg / O1 / Lecture Hall (I02.O1.014) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Peipeng Lin: Thesis Defense:  	Calibrating the Teacher Synapse: Mec
 hanisms and Functional Significance of Presynaptic Inhibition at Hippocamp
 al Mossy Fiber Synapses
URL:https://talks-calendar.ista.ac.at/events/6569
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1786546800@ist.ac.at
DTSTART:20260812T170000
DTEND:20260812T230000
DESCRIPTION:Abstract: On 12 August\, the VISTA Science Experience Center in
 vites you to From Eclipse to Starlight\, a cosmic summer evening at the I
 STA campus in Klosterneuburg.Starting at 6:00 pm\, visitors can enjoy a va
 ried program combining science and music. The ISTA Astro Club opens the ev
 ening with an interactive astronomy talk and quiz. Afterwards\, the total 
 solar eclipse will be shown live on the big screen through a broadcast pro
 vided by the European Space Agency. At 8:30 pm\, Viennese singer songwrite
 r Oskar Haag takes the stage\, while FM4 DJ Phekt provides the musical bac
 kdrop throughout the evening. After dark\, visitors can join the ISTA Astr
 o Club to observe the Perseid meteor shower.Until 8:00 pm\, guests can als
 o visit the Science in the Making exhibition or watch Encounters in the
  Milky Way. Street food and drinks complete the festival atmosphere.
LOCATION:VISTA Science Experience Center\, Klosterneuburg\, ISTA
ORGANIZER:
SUMMARY:From Eclipse to Starlight
URL:https://talks-calendar.ista.ac.at/events/6565
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1786606200@ist.ac.at
DTSTART:20260813T093000
DTEND:20260813T103000
DESCRIPTION:Speaker: Manjunath Javoor\nhosted by Rafal Klajn\nAbstract: Cel
 l motility depends on the protrusive force generated by the actin cytoskel
 eton at the leading edge of cells. In lamellipodia\, thin protrusions at t
 he front of migrating cells\, actin forms higher-order networks with versa
 tile physical properties. Previous studies have hinted at the presence of 
 different sub-populations of filaments and their spatial organization with
 in actin filament networks at the leading edge of migrating cells. Due to 
 limitations of existing experimental methods\, it has not been possible to
  fully describe the complexity of the actin filament populations involved 
 in protrusions at the leading edge.Cryo-electron tomography (cryo-ET) has 
 been used to describe the actin networks in cellular protrusions at single
  filament resolution in 3D. However\, these descriptions have been limited
  to 1-2 μm2 area of the protrusions\, providing merely snapshots of much 
 larger assemblies that span serval tens to hundreds of square microns area
 . Consequently\, they have not provided a holistic overview of the existin
 g variability within actin networks. We therefore lack a comprehensive und
 erstanding of how actin network geometries orchestrate cell migration.To a
 ddress these challenges\, I developed a montage cryo-electron tomography w
 orkflow to obtain three-dimensional views of lamellipodial regions coverin
 g areas of up to 100 μm2 at single-filament resolution. Seamless three-di
 mensional tomogram stitching is achieved by combining neural-network-based
  denoising strategies with novel optical-flow-based algorithms\, thereby p
 reserving filament continuity across large reconstructed volumes. Our comp
 utational analysis pipeline enabled us to vectorize all filaments within t
 hese volumes\, including filaments reaching lengths of up to 4 μm. The da
 ta generated here represent a valuable resource for the actin community\, 
 as they provide one of the most detailed and extensive three-dimensional d
 escriptions of actin filament architecture in the lamellipodium. Specifica
 lly\, they reveal accurate F-actin concentrations\, filament length distri
 butions\, connectivity\, and the spatial organization of filament sub-popu
 lations. These datasets can be used to support and constrain biophysical a
 nd theoretical models of actin network organization\, dynamics\, and force
  generation.
LOCATION:Sunstone Bldg / Ground floor / Big Seminar Room B / 63 seats (I23.
 EG.102) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Manjunath Javoor: Thesis Defense: Large-scale imaging of cellular a
 ctin networks at single-filament resolution using montage cryo-electron to
 mography
URL:https://talks-calendar.ista.ac.at/events/6576
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1786623300@ist.ac.at
DTSTART:20260813T141500
DTEND:20260813T151500
DESCRIPTION:Speaker: Vicente Luis Diaz Melian\nhosted by Kimberly Modic \nA
 bstract: When a Leidenfrost droplet floats on its own vapor layer\, the in
 terplay between vapor pressure\, surface tension\, and gravity determines 
 its shape\, and in the stable regime the underside of the droplet exhibits
  curvature inversion. Using interferometric imaging\, we observe a differe
 nt behavior for a levitated hydrogel sphere. Curvature inversion appears b
 riefly after deposition\, but the continuous vaporization process removes 
 this feature\, leading first to an oscillatory regime and eventually to a 
 steady state without curvature inversion. We demonstrate the essential rol
 e of vaporization in shaping the hydrogel underbelly\, where direct mass l
 oss has a stronger influence than the balance between vapor pressure and e
 lastic forces.
LOCATION:Central Bldg / O1 / Lecture Hall (I02.O1.014) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Vicente Luis Diaz Melian: Thesis Defense: The morphology underneath
  a levitated hydrogel sphere
URL:https://talks-calendar.ista.ac.at/events/6561
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1786629600@ist.ac.at
DTSTART:20260813T160000
DTEND:20260813T170000
DESCRIPTION:Speaker: Klemens Rottner\nhosted by Florian Schur\nAbstract: Ce
 ll migration and proliferation as well as communication and trafficking\, 
 all depend on the fine-tuned and continuous remodeling of actin filaments\
 , which are nucleated and elongated by addition of monomers\, regulated in
  turn by several monomer-binding factors. The most prominent of those cert
 ainly constitute profilin 1\, the largely ubiquitous family member in mamm
 als\, and profilin 2 more enriched in the nervous system. Profilins are we
 ll established as both inhibiting spontaneous actin filament nucleation an
 d promoting formin-dependent actin filament elongation\, but their precise
  cell biological roles are less clear.In this seminar\, I will provide evi
 dence establishing that the presence of any profilin is obligatory for cel
 l growth in both mammals and amoeba\, although minute amounts of the prote
 in are sufficient for mediating migration and actin turnover. I will also 
 show that aside from being essential for formin-dependent filopodia and mi
 crospike formation\, profilin is also crucial for Arp2/3 complex-dependent
  processes. Mathematical modeling reveals how this can be explained. Our d
 ata thus also refute previous suggestions of antagonistic connections betw
 een profilin and Arp2/3 complex. Instead\, profilin emerges as master regu
 lator of both formin- and Arp2/3 complex-dependent actin assembly pathways
  operating directly and indirectly\, respectively.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:
SUMMARY:Klemens Rottner: Defining profilin function in mammalian actin dyna
 mics and cell behaviour 
URL:https://talks-calendar.ista.ac.at/events/6583
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1786975200@ist.ac.at
DTSTART:20260817T160000
DTEND:20260817T170000
DESCRIPTION:Speaker: Kevin Kögler\nhosted by Krzysztof Pietrzak\nAbstract:
  Modern datasets often contain as many variables as observations\, or many
  more\, making classical statistical tools difficult to apply and standard
  machine-learning models hard to understand. To address this problem\, thi
 s thesis develops methods for inference and compression in this high-dimen
 sional regime\, centered on approximate message passing (AMP)\, a family o
 f iterative inference algorithms which are conjecture to be optimal for ma
 ny of these problems.First\, we introduce rotationally invariant generaliz
 ed AMP (RI-GAMP)\, extending AMP beyond independent Gaussian design matric
 es to a broad class of matrices with complex correlations and arbitrary li
 miting spectra. We characterize its performance rigorously through state e
 volution and show that it approaches the performance of Vector AMP while a
 voiding its computationally expensive singular-value decomposition.We then
  study nonlinear autoencoders when the input and compressed dimensions gro
 w proportionally. For Gaussian data\, we derive fundamental limits for one
 -bit compression by shallow two-layer autoencoders\, characterize their op
 timal solutions\, and prove that gradient methods reach them. For structur
 ed data\, however\, a shallow linear decoder may ignore information such a
 s sparsity and behave exactly as it does for Gaussian inputs. Adding nonli
 nearities or depth overcomes this limitation: deeper decoders can learn co
 mputations closely related to AMP and approach optimal reconstruction for 
 a fixed encoder.Finally\, we apply these ideas to predict plasma-protein a
 bundance from UK Biobank individual-level genetic data\, using approximate
 ly 8.4 million genetic variants from roughly 40\,000 individuals. A two-st
 age genetic Vector AMP pipeline first selects a small set of predictive ge
 nomic regions and then fits more detailed linear or tree-based models. Com
 bined with a one-hot representation of the genotype data\, this procedure 
 closes the previously reported average gap between linear and deep-learnin
 g prediction and improves prediction for many proteins in a proteome-wide 
 comparison. 
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 ) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Kevin Kögler: Thesis Defense: Compression and Inference in High Di
 mensions: An Approximate Message Passing Perspective
URL:https://talks-calendar.ista.ac.at/events/6577
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a85953fddda5101667480@ist.ac.at
DTSTART:20260824T140000
DTEND:20260824T150000
DESCRIPTION:Speaker: Farzan Farnia\nhosted by Marco Mondelli\nAbstract: Dee
 p generative models have achieved remarkable success by learning to imitat
 e complex data distributions\, yet distributional fidelity alone does not 
 explicitly promote properties such as diversity\, novelty\, or imagination
 . In this talk\, I will explore how entropy can provide a principled way t
 o extend the conventional objective of generative modeling beyond imitatio
 n. Utilizing pretrained neural network representations\, we introduce a sp
 ectral notion of entropy that captures semantic diversity through the eige
 nvalues of a kernel covariance operator. I will discuss that the concavity
  of this entropy has two important consequences. First\, finite samples sy
 stematically underestimate the entropy of the underlying population\, moti
 vating our study of whether this diversity loss persists in trained genera
 tive models. Our experiments then reveal a consistent entropy gap between 
 standard generative models and their training distributions. Second\, conc
 avity makes entropy superlevel sets convex\, allowing us to show that proj
 ecting a low-diversity model onto a sufficiently high-entropy set can move
  it closer to the true data distribution. Building on these insights\, I w
 ill introduce Imaginative Generative AI (IGA)\, an entropy-regularized fra
 mework that provides a path from diversity correction to deliberate extrap
 olation\, with the entropy of the data defining an Entropy Wall that separ
 ates faithful imitation from the generation of more diverse worlds beyond 
 the observed distribution.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:swiddman@ist.ac.at
SUMMARY:Farzan Farnia: Entropy in Generative AI Models: From Imitation to I
 magination
URL:https://talks-calendar.ista.ac.at/events/6592
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1788163200@ist.ac.at
DTSTART:20260831T100000
DTEND:20260831T110000
DESCRIPTION:Speaker: Anastasiia Teplova\nhosted by Martin Loose\nAbstract: 
 This thesis comprises two parts addressing distinct questions in plant sig
 nalling. Part I examines the proposed nucleotide-cyclase activities of pro
 teins involved in plant hormone signalling. Part II investigates how plant
 s sense gravity and how this information is translated into a directional 
 growth response.In this thesis defense talk\, I will focus on the second p
 art and present my research on the molecular mechanisms underlying root gr
 avitropism. Gravity is perceived in specialized cells called statocytes\, 
 where starch-filled amyloplasts sediment according to the direction of gra
 vity. This leads to auxin redistribution\, which drives differential growt
 h and allows the root to bend towards gravity. LZY proteins provide an imp
 ortant molecular link between statolith sedimentation and the establishmen
 t of cell polarity. However\, how LZY polarity is connected to the downstr
 eam regulation of auxin transport remains incompletely understood.My work 
 investigates this connection\, focusing on the dynamic localization and po
 larization of proteins in root statocytes following root reorientation. In
  particular\, I examine the relationship between LZY proteins and two pote
 ntially interconnected systems: AGC kinases involved in regulating PIN aux
 in transporter activity\, and the RLD–GNOM machinery involved in membran
 e trafficking and PIN polarity. I show that components of both systems dyn
 amically redistribute during the gravitropic response and investigate thei
 r connections with LZY proteins and with each other. Together\, these resu
 lts contribute to understanding how gravity-induced cell polarity is conne
 cted to the regulation of auxin transport during root gravitropism.
LOCATION:Sunstone Bldg / Ground floor / Big Seminar Room B (I23.EG.102) and
  Zoom\, ISTA
ORGANIZER:
SUMMARY:Anastasiia Teplova: Thesis Defense: Chasing the elusive: Investigat
 ing nucleotide cyclase activity in gibberellin and strigolactone signallin
 g\; Cellular mechanisms of gravity sensing and response in roots
URL:https://talks-calendar.ista.ac.at/events/6593
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1788253200@ist.ac.at
DTSTART:20260901T110000
DTEND:20260901T120000
DESCRIPTION:Speaker: Stepan Ovchinnikov\nhosted by Johannes Fink\nAbstract:
  Bacterial adaptation depends not only on the selective environment but al
 so on the genetic background that determines which variants can arise and 
 how they affect fitness. This thesis investigates how genetic background a
 ffects bacterial adaptive capacity by experimentally examining the effect 
 of insertion sequence (IS) elements activity and establishing a strain sys
 tem for future experiments to reveal the role of natural competence.The ma
 in experimental study compared Escherichia coli MG1655 with a derivative l
 acking all 45 chromosomal IS elements\, together with additional strains d
 esigned to separate the effects of IS removal from restoration of the IS-d
 isrupted gene wbbL. Replicate populations were adapted to increasing conce
 ntrations of a five-antibiotic mixture and to each antibiotic individually
 \, and their adaptive responses and evolutionary routes were compared. Und
 er mixture selection\, IS-containing and IS-free populations reached simil
 ar endpoint resistance and acquired similar numbers of mutations\, althoug
 h their mutation spectra differed significantly. IS-driven mutations were 
 rare\, indicating that IS activity contributed little to adaptation under 
 this condition. Adaptation to individual antibiotics produced larger treat
 ment-specific resistance gains and more recurrent mutations in the same lo
 ci across independently evolved populations than adaptation to the antibio
 tic mixture. The contribution of IS-driven mutations varied among antibiot
 ics and was highest under tetracycline selection. Under tetracycline treat
 ment\, IS-containing populations adapted faster and reached higher selecti
 on concentrations than IS-free populations. Inactivation of wbbL partially
  restored the adaptive capacity of the IS-free strain but did not fully el
 iminate the difference\, while IS-containing populations repeatedly access
 ed IS-mediated mutations unavailable to the IS-free strains.Earlier experi
 ments examining adaptation to ethanol\, sodium chloride\, and butanol did 
 not provide reliable evidence for differences between the IS backgrounds. 
 Growth observed at high sodium chloride and butanol concentrations during 
 selection was not retained after stress-free recovery\, whereas turbidosta
 t-based ethanol experiments revealed technical limitations of using the de
 vice for parallel long-term evolution. These results motivated the more ro
 bust antibiotic-selection design. Finally\, an experimental framework was 
 developed to test whether natural competence contributes to the adaptive c
 apacity of Bacillus subtilis. As a first step toward the proposed experime
 nts\, a genotypically verified ΔcomEC strain and characterized fluorescen
 t strains were constructed\, but the evolution experiments remain to be in
 itiated.Together\, these results show that IS elements can expand the repe
 rtoire of accessible mutations without conferring a universal adaptive adv
 antage. Whether IS activity improves adaptation depends on the selective e
 nvironment\, the wider genetic background\, and whether IS-mediated mutati
 ons provide particularly beneficial adaptive routes.
LOCATION:Central Bldg / O1 / Ballroom (I01.O1.006) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Stepan Ovchinnikov: Thesis Defense: The Role of Genetic Background 
 in Bacterial Adaptation
URL:https://talks-calendar.ista.ac.at/events/6601
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1788267600@ist.ac.at
DTSTART:20260901T150000
DTEND:20260901T160000
DESCRIPTION:Speaker: Jonas Ingmanns\nhosted by Monika Henzinger\nAbstract: 
 Precise microscopic models of physical processes are often too complex to 
 be useful for understanding or simulating phenomena on a macroscopic scale
 . The complexity can be drastically reduced if there is a suitable approxi
 mation which still accurately captures the effective large-scale behavior 
 of the underlying model. This thesis contains contributions to the rigorou
 s justification of such large-scale approximations  or three different mo
 dels. Chapter 2 presents joint work with Federico Cornalba\, Julian Fisch
 er\, and Claudia Raithel. We consider a large system of weakly interacting
  particles\, driven by independent Brownian motions. The physicists Dean a
 nd Kawasaki proposed a strongly singular SPDE to describe fluctuations of 
 the particle density. However\, without a suitable regularization\, the De
 an–Kawasaki equation has been shown to be ill-posed in the sense that it
  does not admit martingale solutions for any continuous initial data. We s
 how that a structure-preserving discretization of the Dean–Kawasaki equa
 tion – acting as a suitable regularization – captures the density fluc
 tuations of the particle system up to arbitrary order in the inverse numbe
 r of particles and a discretization error. Chapter 3 presents joint work 
 with Elisa Davoli and Lorenza D’Elia. We consider a magnetic body consis
 ting of a composite material with a random microstructure. The oscillating
  magnetic properties are encoded in the micromagnetic energy functional wh
 ich is restricted to functions taking values on the sphere\, governing the
  observable states of magnetization. We obtain a qualitative stochastic ho
 mogenization result in the form of Γ-convergence. The Γ-limit is a micro
 magnetic energy functional with constant\, deterministic coefficients\, me
 aning that the magnetic body can be treated as if consisting of a single m
 aterial when the microstructure is small enough. On a technical level\, we
 obtain an analogous result replacing the sphere with other sufficiently re
 gular manifolds.Chapter 4 and Chapter 5 present joint work with Julian Fis
 cher. We consider interface motions driven by curvature and a uniform forc
 ing through a stationary field of possibly impenetrable random obstacles s
 atisfying a finite range of dependence assumption. This process models\, e
 .g.\, the motion of dislocation lines or magnetic domain boundaries in mat
 erials with inhibiting impurities. In Chapter 5\, for dimension  = 2\, we 
 introduce an easy-to-check criterion for general obstacle fields which imp
 lies ballistic behavior. More precisely\, this criterion yields an almost 
 guaranteed effective minimum speed on large scales for the interface motio
 n \, with ‘effective’ meaning that enclosures left behind a main front
  can be ignored. In Chapter 4\, for any dimension  ≥ 2\, assuming such a
 n almost guaranteed effective minimum speed\, we obtain a quantitative sto
 chastic homogenization result in any dimension\, proving that the main fro
 nt can be approximated with a constant-speed motion on large scales.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 ) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Jonas Ingmanns: Thesis Defense: On the large-scale behavior of inte
 racting particle systems\, composite magnetic materials\, and interface mo
 tions through random obstacle fields
URL:https://talks-calendar.ista.ac.at/events/6560
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1788433200@ist.ac.at
DTSTART:20260903T130000
DTEND:20260903T140000
DESCRIPTION:Speaker: Nathalie Gruber\nhosted by Jérémie Palacci\nAbstract
 : Bacteria inhabit an extraordinary range of environments\, each shaped by
  its own selective pressures that can fluctuate within seconds to seasons.
  A persistent selective pressure across these environments is imposed by v
 iruses that infect bacteria\, called phages. This ongoing coevolution betw
 een bacteria and phages has led to multiple defense strategies on both sid
 es. Bacteria have defense strategies at multiple levels: at the cell surfa
 ce\, physical barriers such as capsules\, exopolysaccharides\, and recepto
 r modifications limit phage adsorption\, while intracellularly\, molecular
  defense systems degrade or restrict invading genomes. However\, how these
  spatially distinct layers are coordinated during infection remains largel
 y unexplored.To address this\, we investigated the genome-clustered anti-p
 hage defense island of Escherichia coli K-12\, which encodes four anti-pha
 ge systems. We found that a single system dominated intracellular defense 
 across diverse phages. Strikingly\, under sustained phage pressure\, a sec
 ond extracellular layer of defense emerges: phage-induced mucoidy. This is
  a regulator of capsule synthesis (Rcs)-dependent and quorum-sensing-indep
 endent response that generates protective extracellular matrix. This mucoi
 d matrix confers broad resistance\, protecting against 29 of the 31 phages
  tested. Critically\, the two layers are not independent\; the strength of
  the defense system-mediated restriction directly sets the phage dose thre
 shold at which mucoidy is induced. Therefore\, intracellular and extracell
 ular defenses do not operate in isolation but as a single\, quantitatively
  coupled immune response.By revealing a direct mechanistic link between in
 tracellular anti-phage systems and phenotypic switching to mucoidy\, this 
 work reframes bacterial immunity as an integrated\, multi-layered process\
 , with broad implications for phage–host coevolution and for the design 
 of phage therapies against mucoid variants\, which are associated with inc
 reased patient mortality.
LOCATION:Central Bldg / O1 / Ballroom (I01.O1.006) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Nathalie Gruber: Thesis Defense: Genetic Strategies Enabling Bacter
 ial Adaptation to Selective Pressures
URL:https://talks-calendar.ista.ac.at/events/6591
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a6718ef86935830306549@ist.ac.at
DTSTART:20260903T134500
DTEND:20260903T150000
DESCRIPTION:Speaker: Eduardo Fernández Ortuño\nhosted by Lora Sweeney\nAb
 stract: The phenomenal size and cellular diversity of the human cerebral c
 ortex is the outcome of an elaborate developmental program sculpted by evo
 lutionary forces during millions of years. This evolution involved changes
  in neural progenitor cells\, which compared to reptiles and birds acquire
 d the capacity to generate larger numbers of neurons and in greater divers
 ity. Genetic causes of increased progenitor cell proliferation during evol
 ution have been identified\, but mechanisms involved in the diversificatio
 n of neural progenitor cells remain unknown. To address this question\, we
  performed the first integrated\, multi-level\, comparative study of neura
 l progenitor cells and lineages in the embryonic cortex across amniotes. T
 he analysis was focused on four strategic species that cover the spectrum 
 of cortical phenotypes: house snake\, chick\, mouse and ferret. Our result
 s revealed an unsuspected diversity of basal progenitor cell types in chic
 k\, superior to mouse and with similarities to the more complex ferret cor
 tex. Chick dorsal pallial progenitors included subapical and basal Radial 
 Glia\, and co-expressed Pax6 and Tbr2\, similar to ferret but unlike mouse
 \, where these are largely absent. Our findings challenge current concepts
  on the evolutionary trajectory of the cerebral cortex\, revealing a very 
 early diversification of cortical progenitor cell types in amniotes that p
 redated the last common ancestor of mammals and birds.
LOCATION:Sunstone Bldg / Ground floor / Big Seminar Room B / 63 seats (I23.
 EG.102)\, ISTA
ORGANIZER:jgazsi@ist.ac.at
SUMMARY:Eduardo Fernández Ortuño: Don't Put All Your Eggs in the Neocorte
 x: How the small chick dorsal pallium challenges mammalian-centric views o
 n brain cortex evolution
URL:https://talks-calendar.ista.ac.at/events/6573
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1788508800@ist.ac.at
DTSTART:20260904T100000
DTEND:20260904T110000
DESCRIPTION:Speaker: Andreas Ehrmann\nhosted by Paul Schanda\nAbstract: Bio
 logy is overwhelmingly good at designing building blocks that are orchestr
 ated in remarkable processes to enable the functioning of complex organism
 s. Is it possible to achieve similar complexity in nanotechnology? The fie
 ld of self-assembly offers a promising route towards bio-inspired function
 ality. While significant progress has been made in the inverse design of c
 omplex structures\, little is currently known about embedding these struct
 ures with dynamics and functional behavior at levels found in biology. Unl
 ike biology\, we do not have million years of evolution to result in optim
 al behavior. We aspire to discover fundamental design principles in simple
  physical systems by taking an optimization approach that builds up on met
 hods developed by the Machine Learning community to achieve a desired func
 tion. Many future nanotechnologies will need to do more than hold a desig
 ned shape: they will need to move\, switch states\, and interact with othe
 r objects in controlled ways. Is it possible to replicate the precise\, ta
 rgeted energy delivery of ATP hydrolysis in synthetic systems\, where we c
 annot rely on biochemical interactions\, to power synthetic nanomachines? 
 In this thesis\, we develop a mechanical model for a controlled energy-del
 ivery mechanism between bistable nanostructures\, and discover key design 
 features necessary to generate a pathway for efficient energy transduction
 . Inspired by the universality of ATP hydrolysis\, this achievement could 
 serve as a scheme for powering more and more complex tasks. We show how bi
 stable nanostructures can be designed so that their conformational changes
  produce a prescribed behavior. By separating the energetic control of a n
 anoscale switch from the geometric placement of its binding sites\, we ide
 ntify which aspects of its energy landscape can be programmed under realis
 tic constraints. The results provide design principles for turning synthet
 ic nanostructures into functional\, machine-like objects. By demonstrating
  how we can translate the scheme for energy delivery to three-state molecu
 lar machines walking along a track at a very basic level\, we take a first
  step towards performing a task. We reveal a fundamental speed-efficiency 
 tradeoff and important design considerations. This research contributes to
 wards designing nanomachines that might eventually be able to contest with
  the levels of complexity and functionality found in biology.
LOCATION:Central Bldg / O1 / Mondi 2a (I01.O1.008)\, ISTA
ORGANIZER:
SUMMARY:Andreas Ehrmann: Thesis Defense: Biological functionality without b
 iochemistry: designing nanomachines for target behavior 
URL:https://talks-calendar.ista.ac.at/events/6578
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1788951600@ist.ac.at
DTSTART:20260909T130000
DTEND:20260909T140000
DESCRIPTION:Speaker: Andrea Stöllner\nhosted by Jorryt Matthee\nAbstract: 
 Charge accumulation on aerosol particles plays an important role in a vari
 ety of natural and industrial processes. An example is cloud electrificati
 on\, in which collisions between ice crystals and graupel cause large amou
 nts of charge to be exchanged between airborne particles. Optical tweezers
  are a highly specialized tool that can hold a single micrometer-sized air
 borne particle stably in the same position over weeks while measuring its 
 electric charge with elementary-charge resolution. In this work\, we show 
 that the trapping laser can also be used to give charge to the micropartic
 le. Via a two-photon process the particle acquires more and more positive 
 charge\, enabling us to study its electrical behavior from uncharged up to
  multiple hundred elementary charges. By studying the dynamics of such hig
 hly charged particles over days and weeks we find that they spontaneously 
 undergo microdischarges which range from just a few to several hundred ele
 mentary charges. We show that these discharges are triggered by cosmic-ray
  muons which pass through the air close to the particle and supply the ion
 s needed to cause charge loss. Our findings highlight the potential of aer
 osol optical tweezers to provide new insights into microscale charging and
  discharging phenomena\, with implications for both fundamental studies an
 d atmospheric electrification processes.
LOCATION:Central Bldg / O1 / Mondi 3 (I01.O1.010)\, ISTA
ORGANIZER:
SUMMARY:Andrea Stöllner: Thesis Defense: Microscale Electrical Behavior of
  Highly Charged Individual Aerosol Particles Using Optical Tweezers
URL:https://talks-calendar.ista.ac.at/events/6572
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1789635600@ist.ac.at
DTSTART:20260917T110000
DTEND:20260917T120000
DESCRIPTION:Speaker: Krishna Shrinivas\nhosted by Carl Goodrich\nAbstract: 
 Living cells perform remarkable functions that are powered through biomole
 cular networks that interact and react in crowded cellular environments. M
 any biomolecules are highly dynamic\, fluctuating among diverse conformati
 onal ensembles and spatially self-organizing through phase transitions. Ho
 w can cells harness the physics of these dynamic assemblies to sense\, com
 pute\, and respond to their environment? Using design as a lens\, I will e
 xplore how physical principles connect molecular-scale dynamics and self-o
 rganization to enable and constrain biomolecular information processing.
LOCATION:Ballroom / Central Bldg / O1\, ISTA
ORGANIZER:caroline.ernst-petz@ista.ac.at
SUMMARY:Krishna Shrinivas: Cellular computations and decision-making by dyn
 amic biomolecular ensembles
URL:https://talks-calendar.ista.ac.at/events/6607
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1789736400@ist.ac.at
DTSTART:20260918T150000
DTEND:20260918T173000
DESCRIPTION:hosted by Samarth Hawaldar\; Edward-Fulbright Gheorghita\nAbstr
 act: Labs Visited: Fink\, Katsaros\, Modic\, Leonard\, and Hosten
LOCATION:Lab and Office Building West\, ISTA
ORGANIZER:
SUMMARY:Quantum Experimentalist Lab Tours
URL:https://talks-calendar.ista.ac.at/events/6617
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1789983000@ist.ac.at
DTSTART:20260921T113000
DTEND:20260921T123000
DESCRIPTION:Speaker: Lena Schwarz & Jiawei Bao\nhosted by Jorryt Matthee & 
 Martin Hetzer\nAbstract: Lena Schwarz | Mapping Developmental Dynamics of 
 Autism Spectrum DisorderMouse Models at Single-Cell ResolutionAutism spect
 rum disorder (ASD) is associated with a wide range of risk genes\, yet how
  distinct mutations lead to overlapping clinical features remains poorly u
 nderstood. ASD is also diagnosed more often in males than females\, but th
 e molecular basis of this sex disparity remains unclear.We used single-nuc
 leus multi-omics sequencing to simultaneously examine gene expression and 
 chromatin accessibility in 251 samples from eleven monogenic ASD mouse mod
 els. The dataset included both sexes\, two brain regions\, and three devel
 opmental stages. Across models\, ASD-associated mutations delayed radial g
 lial cell progression and transiently affected neural lineage specificatio
 n. The strongest transcriptional alterations occurred during the perinatal
  period\, particularly in excitatory and inhibitory neurons. These changes
  included reduced expression of synaptic and ion-channel-related genes\, p
 otentially reflecting homeostatic adaptations. Although several molecular 
 alterations were shared across models\, each mutation also produced a dist
 inct molecular signature.Convergence was most pronounced at the early post
 natal stage\, a putatively critical period of cortical maturation and refi
 nement. At later developmental stages\, the shared molecular processes  i
 ncreasingly diverged\, identifying the early postnatal period as a key win
 dow of ASD-related molecular vulnerability. We also observed marked sex-sp
 ecific effects\, with females frequently displaying broader transcriptiona
 l dysregulation and larger effect sizes than males.Overall\, our findings 
 reveal dynamic\, developmentally regulated molecular consequences of genet
 ically diverse ASD-associated mutations. They identify both convergent and
  mutationspecific mechanisms\, emphasize the importance of sex-dependent e
 ffects\, and provide a comprehensive view of developmental cellular and mo
 lecular dynamics across models of ASD.____________________________________
 ___________________________________________Jiawei Bao | The Pulsing of th
 e Tropical Climate SystemWeather forecasts keep us prepared for the week a
 head\, while climate projections warn us of long-term changes over coming 
 decades. But what about the weeks and months in between? This middle groun
 d\, known as the subseasonal-to-seasonal timescale\, remains one of the mo
 st challenging frontiers in atmospheric science\, yet it is precisely the 
 timescale that matters most for managing floods\, droughts\, and food secu
 rity. In this talk\, I will walk through how scientists predict weather a
 nd climate\, the tools and models involved\, and why the gap in between ha
 s proven so difficult to bridge. I will then introduce a newly discovered 
 phenomenon in the tropics — the Tropics-Wide Intraseasonal Oscillation (
 TWISO) — a coherent pulse that links tropical weather phenomena across t
 he globe\, not just within one region or system\, on timescales of weeks t
 o months. It looks as if the tropical climate system is pulsing together. 
 By capturing signals that existing frameworks miss\, TWISO offers a promis
 ing new avenue for improving predictability in the tropics\, with potentia
 l benefits for communities most vulnerable to extreme weather.
LOCATION:ISTA | Central Building | Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Lena Schwarz & Jiawei Bao: ISTA PostDoc Award
URL:https://talks-calendar.ista.ac.at/events/6386
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1790074800@ist.ac.at
DTSTART:20260922T130000
DTEND:20260922T180000
DESCRIPTION:Abstract: We are excited to announce the 2nd annual Neuroscienc
 e Faculty Symposium organized by your student neuroscience track represent
 atives!Every neuroscience PI will hold a brief talk discussing their lab'
 s current research. The symposium will include catered breaks! Please als
 o join us for the Pizza Reception following the talks.We look forward to 
 seeing you all there!
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:
SUMMARY:Neuroscience Faculty Symposium
URL:https://talks-calendar.ista.ac.at/events/6589
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a1e9cbf72e58407814214@ist.ac.at
DTSTART:20260922T150000
DTEND:20260922T160000
DESCRIPTION:Speaker: Domenico Cafiero\nhosted by Robert Seiringer\nAbstract
 : Anyons are 2d identical quantum particles with an intermediate exchange 
 symmetry characterized by representations of the braid group. In the abeli
 an case\, they can be modelled through the so-called magnetic representati
 on\, namely as a system of bosons with an Aharonov-Bohm flux attached to e
 ach particle.In this talk\, I will discuss the construction of self-adjoin
 t Hamiltonians\, different from the Friedrichs realization\, for a system 
 of three abelian anyons. I will focus in particular on the Ter-Martirosyan
 -Skornyakov extensions. This family of Hamiltonians turns out to be parame
 trized by a suitable boundary operator\; I will present a complete classif
 ication of its self-adjoint realizations and compute the negative spectrum
  for the specific case of interest. These results shed light on the possib
 le occurrence of Thomas instability in the three-anyon model. Joint work w
 ith Michele Correggi (PoliMi) and Davide Fermi (PoliMi).
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:boosthui@ist.ac.at
SUMMARY:Domenico Cafiero: On the three-body Hamiltonian for abelian anyons
URL:https://talks-calendar.ista.ac.at/events/6566
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1790092800@ist.ac.at
DTSTART:20260922T180000
DTEND:20260922T190000
DESCRIPTION:Speaker: Klaus-Robert Müller\nhosted by ÖAW\nAbstract: Abstra
 ctIn recent years\, machine learning (ML) and artificial intelligence (AI)
  methods have begun to play a more and more enabling role in the sciences 
 and in industry. In particular\, the advent of large and/or complex data c
 orpora has given rise to new technological challenges and possibilities. I
 n his talk\, Müller will touch upon the topic of ML applications in the s
 ciences\, in particular in medicine and if time permits also in chemistry.
  He will also discuss possibilities for extracting information from machin
 e learning models to further our understanding by explaining nonlinear ML 
 models. Finally\, Müller will briefly discuss perspectives and limitation
 s.BioKlaus-Robert Müller is Professor for Machine Learning at TU Berlin a
 nd at Korea University\, Seoul. He is director of BIFOLD – one of 5 perm
 anently funded German national AI centers. He is a member of Leopoldina\
 , BBAW and Acatech and an external scientific member of the Max-Planck S
 ociety. Among others he received the Berlin Science prize\, the Vodafone I
 nnovation Award\, the Hector Science award\, the Feynman award\, the IEEE 
 CIS Neural Network Pioneer Award and the Gottfried Wilhelm Leibniz prize. 
 Consecutively from 2019 on he became ISI Highly Cited Researcher. His rese
 arch interests are in AI for the sciences and in the foundations of AI.Pho
 to: © Bifold
LOCATION:Dr. Ignaz Seipel-Platz 2\, 1010 Vienna\, Austria\, ISTA
ORGANIZER:events@ista.ac.at
SUMMARY:Klaus-Robert Müller: AI for the Sciences: towards Understanding
URL:https://talks-calendar.ista.ac.at/events/6288
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6a8ec4a176df3637528802@ist.ac.at
DTSTART:20260923T130000
DTEND:20260923T140000
DESCRIPTION:Speaker: Fabian Gundlach\nhosted by Tim  Browning\nAbstract: We
  give asymptotics for the total number of interlaced simultaneous ordered 
 factorizations of integers n_1 <= X_1 and n_2 <= X_2. The answer is surpri
 sing.
LOCATION:Central Bldg / O1 / Mondi 4 (01.01.011 (Mondi4 is next to Mondi Th
 ree))\, ISTA
ORGANIZER:boosthui@ist.ac.at
SUMMARY:Fabian Gundlach: Counting interlaced factorizations
URL:https://talks-calendar.ista.ac.at/events/6639
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1790240400@ist.ac.at
DTSTART:20260924T110000
DTEND:20260924T120000
DESCRIPTION:Speaker: Prof. Yves Geerts\nhosted by Rafal Klajn\nAbstract: Lo
 uis Pasteur and Pierre Curie dreamed of directing chiral symmetry breaking
  using external magnetic and electric fields. [Chem. Rev. 1998\, 98\, 2391
 ] Their attempts failed due to time-inversion symmetry\, theoretically exp
 lained by Laurence Barron. [JACS 1986\, 108\, 5539] Dissipative non-equili
 brium conditions break this symmetry and allow the separation of enantiome
 rs under the influence of erroneous chirality\, as recently demonstrated b
 y Ron Naaman and Francesco Tassinari. [Chem. Sci. 2019\, 10\, 5246. Cryst.
  Growth Des. [2021\, 21\, 2925] With my team\, we have undertaken a resear
 ch project to further our understanding by directing deracemization toward
 s R or S enantiomers using chirality-induced spin selectivity (CISS). [Acc
 . Chem. Res.] [2020\, 53\, 2659] I will report on our latest results and t
 he prospects for realizing Pasteur and Curie's long-held dream.
LOCATION:Seminar Room C | Moonstone\, ISTA
ORGANIZER:hcai@ist.ac.at
SUMMARY:Prof. Yves Geerts: Spin-directed Chiral Symmetry Breaking
URL:https://talks-calendar.ista.ac.at/events/6579
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:6aa7cc7f86cf5144155787@ist.ac.at
DTSTART:20260924T140000
DTEND:20260924T150000
DESCRIPTION:Speaker: Pavel Arkhipov\nAbstract: Continual counting under pur
 e differential privacy is one of the simplest and most well-studied proble
 ms in the continual observation model. Given a binary stream $x_1\, \\ldot
 s\, x_n \\in \\{0\,1\\}$\, the goal is to release\, at each time $t$\, an 
 approximation to the prefix sum $\\sum_{i=1}^t x_i$. The entire output seq
 uence must satisfy $\\epsilon$-differential privacy\, while making the acc
 uracy as good as possible. We consider the maximum expected squared error 
 over all times $t$ as our accuracy score. Very recently\, it was shown tha
 t the correct asymptotics for this error is $\\Theta(\\epsilon^{-2} \\log^
 3 n)$ for factorization-based mechanisms.We give a construction using a ge
 neral matrix factorization mechanism\, improving the leading constant for 
 the mean squared error. The mechanism starts from a good-quality low-dimen
 sional factorization and lifts this factorization to arbitrarily large dim
 ensions.On the lower-bound side\, we show a very simple $\\Omega(\\epsilon
 ^{-2}\\log^3 n)$ lower bound for the special case of factorizations whose 
 matrices have entries in {0\, 1}.This talk covers a subset of our paper wi
 th Nikita Kalinin (https://arxiv.org/abs/2607.08963)
LOCATION:Mondi Seminar Room 3\, Central Building\, ISTA
ORGANIZER:joanders@ist.ac.at
SUMMARY:Pavel Arkhipov: TCS Seminar - Differentially Private Continual Coun
 ting via Matrix Factorization: Constructions and Lower Bounds
URL:https://talks-calendar.ista.ac.at/events/6619
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1790341200@ist.ac.at
DTSTART:20260925T150000
DTEND:20260925T180000
DESCRIPTION:hosted by ISTA\nAbstract: Join a lively peertopeer event design
 ed for postdocs navigating the job search.Share practical tips\, vent comm
 on frustrations\, celebrate successes\, and exchange honest advice — all
  in a relaxed speednetworking format that reminds you: you’re not alone 
 in this process!Food\, fun\, facilitation\, and meaningful connections inc
 luded.The Maria Gugging hills are waiting for you!
LOCATION:Moonstone Seminar Room F+G\, ISTA
ORGANIZER:boris.cesnik@ista.ac.at
SUMMARY:PAW Closure Networking Event
URL:https://talks-calendar.ista.ac.at/events/6495
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1790587800@ist.ac.at
DTSTART:20260928T113000
DTEND:20260928T123000
DESCRIPTION:Speaker: Francesco Locatello\nhosted by Christoph Lampert\nAbst
 ract: Causality at Machine Learning Scale and ComplexityDistinguishing coi
 ncidence from cause-and-effect relationships is a central challenge in AI 
 (and science): which patterns just co-occur\, and which signal causality? 
 Statistical causality offers a rigorous framework for this question\, but 
 it assumes clean\, low-dimensional\, structured data\, which clashes with 
 the raw\, high-dimensional observations of machine learning applications\,
  including in science. In this talk\, I will present how we can now learn 
 causal structure directly from unstructured data using deep learning\, bri
 dging between the modeling power of causality and the scalability properti
 es of machine learning. I will also highlight some cross-disciplinary coll
 aborations my group has built\, uniquely enabled by ISTA. 
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Francesco Locatello: Tenure Talk
URL:https://talks-calendar.ista.ac.at/events/6548
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1790928000@ist.ac.at
DTSTART:20261002T100000
DTEND:20261002T110000
DESCRIPTION:Speaker: Elisa De Ranieri\nhosted by Charles Roques-Carmes\nAbs
 tract: Publishing in influential journalsEver wondered how high-impact jou
 rnals select content for publication and how peer review works? In this ta
 lk\, I will discuss the editorial process at these journals\, which typica
 lly rely on professional editors\, focusing in particular on the Cell Pres
 s portfolio and introducing Newton\, our flagship physics journal. I will
  also share my views on current trends in scientific publishing\, and prov
 ide tips on how to maximise the fit of your manuscript for high-impact jou
 rnals and on how to deliver an appropriate reviewer report if you are invi
 ted to review a manuscript.  Elisa De Ranieri\, Editor-in-Chief\, Newto
 nElisa obtained her PhD in physics from the University of Cambridge and wo
 rked as a research scientist at the Hitachi Cambridge Laboratory. Her expe
 rimental work on semiconductor spintronics included the design\, fabricati
 on\, and characterization of devices by magneto-transport and magneto-opti
 cal measurements. Elisa joined Cell Press in 2021 as Head of Author Experi
 ence and Research Integrity after acquiring extensive editorial and publis
 hing experience at the Nature portfolio\, working amongst other roles as a
 n editor for Nature Nanotechnology\, Nature Energy\, and as Editor-in-ch
 ief for Nature Communications. In 2023-24 she was the Director of Author 
 Experience for Cell Press\, and became the founding Editor-in-chief of Ne
 wton in 2024.
LOCATION:Heinzel Seminar Room\, ISTA
ORGANIZER:omerhalil.unal@ista.ac.at
SUMMARY:Elisa De Ranieri: Publishing in influential journals
URL:https://talks-calendar.ista.ac.at/events/6610
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1791192600@ist.ac.at
DTSTART:20261005T113000
DTEND:20261005T123000
DESCRIPTION:Speaker: Friedrich Stricker & Yuval Wigderson\nhosted by Mikhai
 l Lemeshko\nAbstract: Friedrich Stricker |Beyond On/Off: Multistate Molecu
 les and MaterialsA slime mold with no brain and no nervous system can stil
 l remember: Physarum polycephalum reinforces the tubes of its cytoplasmic 
 network along paths that once carried nutrient flow\, so a stimulus encoun
 tered minutes ago changes how the organism responds to a stimulus now. His
 tory is written directly into the material's structure. Synthetic material
 s have rarely matched this — not because they can't respond to a cue\, b
 ut because most are built to give one answer\, not many\, and to forget th
 e moment the stimulus is gone.At the root of that limitation is a simple f
 act about energy landscapes. In a binary switch\, a stimulus drives the sy
 stem along one path — on to off\, off to on — so the response is alway
 s the same regardless of how it got there. In a multistate system\, the sa
 me stimulus can drive the system along different paths depending on kineti
 cs\, local environment\, and history: the landscape stops being a fixed tw
 o-well problem and becomes something the material can be routed through.Ge
 tting there means tracing a single design logic across three length scales
 . At the molecular level\, multistate photoswitches give us control over k
 inetics\, absorption\, and mechanistic pathways — the raw vocabulary of 
 reactivity. Organizing those switches within ordered\, multiphase material
 s – often liquid crystal elastomers – lets us govern how changes at th
 e molecular level propagate into changes in structural order. And by shapi
 ng how these material meet a stimulus — through its geometry — we conv
 ert molecular-scale reactivity into coordinated\, purposeful behavior at t
 he macroscale. Molecular design\, material organization\, and geometry are
 n't separate levers\; each constrains and amplifies the next\, and it's th
 is chain that lets us engineer function rather than just response.This cha
 in — molecule\, assembly\, geometry — is a first step toward a larger 
 goal: materials in which a past stimulus leaves a physical trace that bias
 es the path taken by future stimuli\, built not from external control but 
 from molecular architecture that intrinsically encodes state. Programming 
 reactivity\, assembly\, and geometry together is how we move from isolated
  switches to physically intelligent\, multifunctional matter._____________
 ___________________________________________________________________Yuval W
 igderson |Finding Structure in ChaosPareidolia refers to the human tenden
 cy to see patterns in unstructured chaos. Examples of pareidolia can range
  from the benign (seeing constellations in the night sky) to the destruct
 ive (gambling one's savings on the imagined patterns of a roulette wheel'
 s outcomes).However\, sometimes the patterns really are there! In fact\, 
 in many cases\, we can prove this mathematically: no matter how complex an
 d chaotic a system may seem\, it must contain some given structure within 
 it. In this talk\, I will give a gentle introduction to Ramsey theory\, th
 e fascinating area of mathematics that studies such theorems\, and discuss
  some of the major questions we still cannot answer.
LOCATION:ISTA | Central Building | Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Friedrich Stricker & Yuval Wigderson: Inaugural Lecture
URL:https://talks-calendar.ista.ac.at/events/6357
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:68498ab73a3db369081593@ist.ac.at
DTSTART:20261006T110000
DTEND:20261006T120000
DESCRIPTION:Speaker: Morten Kjaergaard\nhosted by Johannes Fink\nAbstract: 
 I will discuss recent results from our lab on developing a tight control-a
 nd-feedback loop between rapid FPGA-based advanced logic and superconducti
 ng qubit control\, which enables qubit characterization\, optimization\, g
 ate benchmarking\, and parameter estimation on millisecond wall-clock time
 scales. I will introduce our work on a suite of sparse-sampling and on-FPG
 A inference methods\, including efficient estimators for exponential and s
 inusoidal response functions as well as on-FPGA implementations of NelderM
 ead optimization\, golden-section search and an adaptive Bayesian updating
  algorithm. With this approach\, we estimate T1 in a few milliseconds and 
 find highly surprising dynamics at these rapid timescales\, we optimize re
 adout parameters in roughly 100 ms\, we optimize pulse amplitudes in 1 ms\
 , we perform Clifford randomized benchmarking in 107 ms\, and sustain more
  than 74\,000 consecutive recalibrations during a 6-hour closed-loop run. 
 These approaches enable in situ recalibration that can track evolving qubi
 t dynamics and enable new approaches to maximizing superconducting qubit p
 rocessor performance and reveal new physics of state-of-the-art quantum pr
 ocessors.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:swiddman@ist.ac.at
SUMMARY:Morten Kjaergaard: Superconducting qubit control on millisecond tim
 escales: from rapid feedback to new qubit dynamics
URL:https://talks-calendar.ista.ac.at/events/6555
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1791797400@ist.ac.at
DTSTART:20261012T113000
DTEND:20261012T123000
DESCRIPTION:Speaker: Suvi Gezari Stock\nhosted by Zoltan Haiman
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Suvi Gezari Stock: Institute Colloquium | Suvi Gezari Stock
URL:https://talks-calendar.ista.ac.at/events/6590
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1792141200@ist.ac.at
DTSTART:20261016T110000
DTEND:20261016T120000
DESCRIPTION:Speaker: Justus Bruggenjurgen\nhosted by Julian Leonard\nAbstra
 ct: TBA
LOCATION:Sunstone Bldg / Ground floor / Big Seminar Room A\, ISTA
ORGANIZER:Stephanie.Dolot@ist.ac.at
SUMMARY:Justus Bruggenjurgen: Quantum Seminar | Justus Bruggenjurgen
URL:https://talks-calendar.ista.ac.at/events/6608
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1792393200@ist.ac.at
DTSTART:20261019T090000
DTEND:20261021T170000
DESCRIPTION:hosted by Jorryt Matthee\nAbstract: First light on the ELT is n
 ominally three years away. Time is ticking for us to start thinking about 
 how to best use the ELT. The Austrian Academy of Science is financing a se
 ries of 5 yearly meetings leading up to first light. The main aim is to br
 ing together the future ELT community and to help build the science cases 
 and proposals that will shape the ELT’s initial observing periods. A key
  goal of the meeting is to connect the instrument builders with the future
  users of the ELT\, in order to educate the community for how to best make
  use of these instruments once they are on-sky.This three-day meeting aims
  to cover numerous discussions on early ELT science topics across instrume
 nts\, as well as simulated observations that guide observing strategies. T
 he meeting will complement traditional scientific presentations with a sim
 ulation hackathons in the afternoons.For 2026\, the scientific focus is on
  science and simulations at the edge of the sensitivity limits enabled by 
 the large collecting power of the ELT’s 40m mirror.
LOCATION:Moonstone Building\, ISTA
ORGANIZER:niels.eelman@ista.ac.at
SUMMARY:Austrian ELT Workshop
URL:https://talks-calendar.ista.ac.at/events/6616
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1792402200@ist.ac.at
DTSTART:20261019T113000
DTEND:20261019T123000
DESCRIPTION:Speaker: Wilfrid Jean Louis\nhosted by AURAS\nAbstract: Wilfrid
  Jean Louis | AURAS Survey 2026: The PhD and Postdoc Experience at ISTATh
 e AURAS 2026 survey gathered feedback from more than 220 PhD students and 
 postdocs at ISTA\, 45% of the institute’s PhD students participated. The
  survey explored different aspects of the experience at ISTA\, including r
 esearch and working environments\, workload and well-being\, teaching and 
 courses\, career development\, workplace safety\, institutional support\, 
 representation\, and track communities. In this colloquium\, AURAS will p
 resent the main findings of the survey\, highlighting both positive aspect
 s of the institute experience and areas where students and postdocs see op
 portunities for improvement. The presentation will also discuss difference
 s across tracks and identify themes that emerged across the institute as a
  whole.
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Wilfrid Jean Louis: Special Colloquium | AURAS | Wilfrid Jean Louis
URL:https://talks-calendar.ista.ac.at/events/6614
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1794220200@ist.ac.at
DTSTART:20261109T113000
DTEND:20261109T123000
DESCRIPTION:Speaker: Lauren O'Connell\nhosted by Lora Sweeney\nAbstract: Ti
 tle | Lessons from Poison Frogs on Ecological Tuning of Animal Behavior a
 nd PhysiologyAbstract |Behavior and physiology are the substrates of natu
 ral selection. Our overarching goal is to understand how new traits in phy
 siology and social behavior have evolved from existing genetic and cellula
 r components using poison frogs as research organisms. First\, we want to 
 understand how organisms evolve ways to evade predation by using natural p
 roducts that target the nervous system. Animals with a rich diversity of c
 hemical defenses must also protect their own nervous systems from toxicity
 . We recently discovered toxin sponge proteins that bind deadly toxins and
  transport them to specific locations in poison frogs. Such a system is ri
 pe for reverse engineering drug carriers to better understand how chemical
  defenses evolve. Second\, we want to understand how new social behaviors 
 evolve through changes in nervous system function using a comparative\, or
 ganismal approach. We have established poison frog tadpoles as a model sys
 tem for infant social behavior\, where species have evolved new communicat
 ion and social behaviors based on their rearing environments. Together\, t
 hese research avenues are enabling us to understand the design principles 
 of chemical defense and social behaviors.
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Lauren O'Connell: Lessons from Poison Frogs on Ecological Tuning of
  Animal Behavior and Physiology
URL:https://talks-calendar.ista.ac.at/events/6550
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1794825000@ist.ac.at
DTSTART:20261116T113000
DTEND:20261116T123000
DESCRIPTION:Speaker: Vivian Kuperberg & Carla Fernandez-Rico\nhosted by Mik
 hail Lemeshko
LOCATION:ISTA | Central Building | Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Vivian Kuperberg & Carla Fernandez-Rico: Inaugural Lecture | Vivian
  Kuperberg & Carla Fernandez-Rico
URL:https://talks-calendar.ista.ac.at/events/6389
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:68498ab73a3f1770646428@ist.ac.at
DTSTART:20261117T110000
DTEND:20261117T120000
DESCRIPTION:Speaker: Sebastian Hofferberth\nhosted by Julian LÃ©onard\nAb
 stract: TBA
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:sdolot@ist.ac.at
SUMMARY:Sebastian Hofferberth: Quantum Colloquium | Sebastian Hofferberth
URL:https://talks-calendar.ista.ac.at/events/6558
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1795429800@ist.ac.at
DTSTART:20261123T113000
DTEND:20261123T123000
DESCRIPTION:Speaker: Kim Modic\nhosted by Mikhail Lemeshko
LOCATION:ISTA | Central Building | Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Kim Modic: Tenure Talk | Kim Modic
URL:https://talks-calendar.ista.ac.at/events/6390
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1795593600@ist.ac.at
DTSTART:20261125T090000
DTEND:20261125T170000
DESCRIPTION:hosted by Dan Alistarh\nAbstract: Join us for the second BilA
 I Industry Day at the Institute of Science and Technology Austria (ISTA)
  in Klosterneuburg and get in touch with AI research to foster strong pa
 rtnerships and accelerate real-world innovation. Leading experts from acad
 emia and industry will come together to share insights\, showcase results 
 and explore new pathways for bilateral collaboration in AI.Date: November
  25\, 2026Venue: Institute of Science and Technology Austria\, 3400 Klost
 erneuburgRegistration details and the programme will follow soon. What to
  expect:Updates for key industry players on ongoing research and results 
 from Bilateral AINetworking OpportunitiesInsights into related industrial
  research and development activities:Keynote speeches from industry and re
 searchTalks and discussionsPoster sessionsBe part of shaping a shared AI f
 uture - grounded in research\, driven by innovation.
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:events@ista.ac.at
SUMMARY:BilAI Industry Day 2026
URL:https://talks-calendar.ista.ac.at/events/6602
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1796639400@ist.ac.at
DTSTART:20261207T113000
DTEND:20261207T123000
DESCRIPTION:Speaker: Daniel Robert\nhosted by Scott Waitukaitis
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Daniel Robert: Institute Colloquium | Daniel Robert
URL:https://talks-calendar.ista.ac.at/events/6551
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1797244200@ist.ac.at
DTSTART:20261214T113000
DTEND:20261214T123000
DESCRIPTION:Speaker: Monika Visan & Simone Fatichi
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Monika Visan & Simone Fatichi: Inaugural Lecture | Monika Visan & S
 imone Fatichi
URL:https://talks-calendar.ista.ac.at/events/6552
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T011831Z
UID:1800268200@ist.ac.at
DTSTART:20270118T113000
DTEND:20270118T123000
DESCRIPTION:Speaker: Lora Sweeney\nhosted by Mario de Bono
LOCATION:ISTA | Central Building | Raiffeisen Lecture Hall\, ISTA
ORGANIZER:diana.zubcevic@ista.ac.at
SUMMARY:Lora Sweeney: Tenure Talk | Lora Sweeney
URL:https://talks-calendar.ista.ac.at/events/6387
END:VEVENT
END:VCALENDAR
