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DTSTAMP:20260427T115912Z
UID:59ad282ce3101738784166@ist.ac.at
DTSTART:20170927T123000
DTEND:20170927T133000
DESCRIPTION:Speaker: Ulrich Technau\nhosted by Nick Barton\nAbstract: How c
 omplex animal body plans could arise in evolution is one of the fundamenta
 l questions in biology. We address this question by investigating the unde
 rlying genomic\, molecular and developmental processes that led to the div
 ersification of animal body plans. We use cnidarians (jellyfish\, corals a
 nd anemones) as model organisms to understand the evolution of key bilater
 ian features: bilaterality\, central nervous systems and three germ layers
 . Our approaches to these questions are comparative and functional genomic
 s in combination with developmental biology: The sequenced genome of the s
 ea anemone Nematostella vectensis revealed many genes usually associated w
 ith the formation of the two body axes\, the three germ layers and the ner
 vous system in Bilateria and we are now studying their function by means o
 f overexpression\, morpholino-mediated knockdown\, CRISPR/Cas9 knockouts a
 nd transgenics. Since the presence of these genes does not necessarily enf
 orce the formation of the structure they are responsible for in bilaterian
 s\, the difference between cnidarians and bilaterians is likely in the gen
 e regulatory network\, both on the transcriptional level as well as on the
  post-transcriptional level. In order to address the question how gene reg
 ulatory networks could evolve\, we established a number of molecular tools
  and genomic resources for Nematostella vectensis.
LOCATION:I22 Lakeside View (I22.01)\, ISTA
ORGANIZER:cfraisse@ist.ac.at
SUMMARY:Ulrich Technau: Evolution of transcriptional and post-transcription
 al regulation: insights from a sea anemone
URL:https://talks-calendar.ista.ac.at/events/834
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