BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20170326T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
END:DAYLIGHT
BEGIN:STANDARD
DTSTART:20171029T020000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10
TZNAME:CET
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20260427T194926Z
UID:599bf1222dc16755348989@ist.ac.at
DTSTART:20171019T110000
DTEND:20171019T120000
DESCRIPTION:Speaker: Nikolaus Grigorieff\nAbstract: The development of elec
 tron cryo-microscopy (cryo-EM) to visualize macromolecules and their assem
 blies has been significantly accelerated in the last five years by the int
 roduction of direct detectors. It is now almost routine to obtain near-ato
 mic resolution structures of non-crystalline samples (single particles) of
  purified material\, often leading to atomic models of the molecules. More
  irregular biological structures\, such as cellular compartments and organ
 elles\, can also be reconstructed\, using electron tomography\, but the re
 solution is limited to about 2 nm unless averaging techniques can be appli
 ed. It is therefore difficult to build reliable atomic models of these lar
 ger structures using tomography data. I will describe a new cryo-EM approa
 ch that allows the precise placement of molecules of known atomic structur
 e into the context of more crowded environments. This approach\, therefore
 \, has the potential to yield atomic models of more complex biological ass
 emblies of unique and irregular structure.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:bkunes@ist.ac.at
SUMMARY:Nikolaus Grigorieff: Finding needles in haystacks – A new approach
  to template matching
URL:https://talks-calendar.ista.ac.at/events/807
END:VEVENT
END:VCALENDAR