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DTSTART:20190331T030000
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DTSTART:20181028T020000
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BEGIN:VEVENT
DTSTAMP:20260404T015759Z
UID:1542639600@ist.ac.at
DTSTART:20181119T160000
DTEND:20181119T170000
DESCRIPTION:Speaker: Molly Przeworski\nhosted by Nick Barton\nAbstract: Mei
 otic recombination is a fundamental genetic process that generates new com
 binations of alleles on which natural selection can act and ensures the pr
 oper alignment and segregation of chromosomes. Recombination events are in
 itiated by double strand breaks deliberately inflicted on the genome durin
 g meiosis. As I will discuss\, in vertebrates\, there appear to be two mai
 n mechanisms by which the locations of these double strand breaks are spec
 ified: through binding of the gene PRDM9 or by localization to promoter-li
 ke features of the genome.  I will present our recent work linking these 
 two mechanisms to dramatic differences in the evolutionary dynamics of rec
 ombination hotspots\, and draw out potential implications for hybridizatio
 n between closely related species.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:arinya.eller@ist.ac.at
SUMMARY:Molly Przeworski: An evolutionary perspective on meiotic recombinat
 ion in vertebrates
URL:https://talks-calendar.ista.ac.at/events/713
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