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DTSTART:20180325T030000
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DTSTART:20181028T020000
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BEGIN:VEVENT
DTSTAMP:20260405T190834Z
UID:1537192800@ist.ac.at
DTSTART:20180917T160000
DTEND:20180917T170000
DESCRIPTION:Speaker: John O'Keefe\nhosted by Peter Jonas\nAbstract: The Hip
 pocampal Formation contains different types of spatial cells (place\, head
 -direction\, boundary\, and grid cells) which together make up a cognitive
  mapping system. The cognitive map enables an animal to locate itself and 
 objects such as food and water in a familiar environment\, and to navigate
  towards or away from particular locations\, for example\, those containin
 g food or danger respectively. There are several behavioral testing paradi
 gms for assessing an animal’ s knowledge of spatial location and its per
 formance on tests of spatial navigation. Foremost amongst the latter is th
 e Morris Water Maze which\, although extremely successful\, has several dr
 awbacks for the assessment of behavior and perhaps more importantly is not
  ideally suited for single unit recording. I will describe a new behaviora
 l testing apparatus\, the Honeycomb Maze\, which overcomes many of these d
 isadvantages. In addition to describing several spatial factors influencin
 g successful performance on this maze\, I will describe the performance of
  animals with hippocampal damage and discuss preliminary data on the use o
 f the maze to study place cell activity.In addition to providing inputs fo
 r the construction of place representations\, the grid cells appear to be 
 good candidates to provide the distance metric for the map. In the second 
 part of my talk\, I will review recent evidence from our laboratory in whi
 ch we distorted the shape of the enclosure. The results suggest that the g
 rid cells are a subset of a more extensive group of spatially periodic EC 
 cells and that they might not be able to provide the metric for the cognit
 ive map in all environments and under all circumstances.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:arinya.eller@ist.ac.at
SUMMARY:John O'Keefe: How rats navigate: recent studies on hippocampal plac
 e and entorhinal grid cells
URL:https://talks-calendar.ista.ac.at/events/705
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