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DTSTAMP:20260428T233019Z
UID:59479aa2b9d0e969251905@ist.ac.at
DTSTART:20170719T130000
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DESCRIPTION:Speaker: Fabienne Jesse\nAbstract: Abstract:\nThe lac operon\, 
 a genetic module relevant for lactose metabolism\, is a classic model syst
 em for bacterial gene regulation. The lac operon has been studied extensiv
 ely in E. coli\, perhaps the best studied bacterium on the planet. Yet\, n
 ot much is known about the ecology of E. coli and its life outside the lab
 oratory. E. coli  is typically found in the gut of mammals\, but has been 
 found in soil and water environments as well\; little is known about its l
 ife in these latter environments. The natural diversity of the lac operon 
 outside the laboratory\, its role in the ecology of E. coli\, and the sele
 ction pressures it is exposed to\, are similarly unknown.\nFabienne has ex
 plored the genetic diversity\, phylogenetic history and signatures of sele
 ction of the lac operon across 20 natural isolates of E. coli and divergen
 t clades of Escherichia\, comparing lac operons of isolates from humans wi
 th those of environmental isolates. \nFurthermore\, she tried to identify 
 the natural genetic variation relevant for phenotype and fitness in the la
 c operon\, comparing growth rate on lactose and LacZ activity of the lac o
 perons of these wild isolates in a common genetic background.\n\nShort bio
 :\nFabienne Jesse completed a Propedeuse in Philosophy at the University o
 f Leiden\, a BSc in Biology at the Free University Amsterdam and a MSc in 
 Animal Biology at the University of Leiden\, before joining IST Austria in
  September 2011. She has done her bachelor's research project on visual at
 tention in humans at the Netherlands Institute for Neuroscience\, and two 
 master's research projects at the University of Leiden\, Netherlands\, one
  on adaptation and diversification in P. fluorescens in the Evolutionary B
 iology and Microbiology groups\, and one investigating diurnal patterns of
  singing and song preference in zebra finches in the Behavioural Biology g
 roup. She has published her findings of the latter project with Katharina 
 Riebel in the journal Behavioural Processes in 2012
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:sseider@ist.ac.at
SUMMARY:Fabienne Jesse: Thesis Defense Fabienne Jesse (Bollback Group): The
  Lac Operon in the Wild
URL:https://talks-calendar.ista.ac.at/events/678
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