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DTSTART:20270328T030000
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DTSTAMP:20261027T152042Z
UID:1793696400@ist.ac.at
DTSTART:20261103T100000
DTEND:20261103T110000
DESCRIPTION:Speaker: Jeremy S. Dasen\nhosted by Sweeney Group\nAbstract: Th
 e vertebrate spinal cord and peripheral nervous system contain remarkably 
 diverse neuronal subtypes that coordinate essential functions\, including 
 locomotion\, breathing\, posture\, and balance. Studies of spinal motor an
 d sensory neuron specification have revealed fundamental mechanisms of neu
 ronal diversification\, many of which are shared across the central nervou
 s system and conserved throughout vertebrate evolution. Comparative analys
 es across species have further illuminated how evolutionary modifications 
 to these developmental programs contribute to the emergence of specialized
  motor behaviors and sensory functions. n this talk\, I will discuss the d
 evelopmental origins of neuronal subtypes essential for limb-based locomot
 ion and the molecular mechanisms underlying their evolution. I will presen
 t recent work examining the genetic programs that establish sensory neuron
  diversity and the relative contributions of intrinsic transcriptional mec
 hanisms and extrinsic target-derived signals to the assembly of somatosens
 ory circuits. These findings reveal how conserved neuronal architectures c
 an emerge through flexible molecular strategies. Finally\, I will explore 
 how early developmental programs establish the anatomical and functional p
 roperties of motor neuron subtypes across aquatic and terrestrial vertebra
 tes\, providing insights into both the ancestral origins and evolutionary 
 diversification of sensorimotor circuits.
LOCATION:Moonstone Bldg\, Ground floor\, Seminar Room G\, ISTA
ORGANIZER:
SUMMARY:Jeremy S. Dasen: Ancestral and Evolutionarily Flexible Mechanisms o
 f Sensorimotor Circuit Development
URL:https://talks-calendar.ista.ac.at/events/6724
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