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DTSTART:20170326T030000
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DTSTAMP:20260429T024541Z
UID:5947833bcf4f7854305082@ist.ac.at
DTSTART:20170627T133000
DTEND:20170627T143000
DESCRIPTION:Speaker: Giselle Cheung-Johnson\nhosted by Simon Hippenmeyer\nA
 bstract: In the central nervous system\, neuroglia cells\, also known as g
 lial cells or simply glia\, refer to a diverse population of cells includi
 ng astrocytes\, oligodendrocytes\, and microglia. While neurons are capabl
 e of forming synaptic connections crucial for direct transmission of infor
 mation across the brain\, glial cells have been traditionally thought to p
 lay only passive supporting roles. However\, mounting evidence has reveale
 d that they are indeed active players in neural functions. At cellular lev
 el\, they are able to sense and respond quickly to synaptic changes using 
 receptors and transporters of neurotransmitters or release gliotransmitter
 s. This is facilitated by their small size and highly motile fine processe
 s making them perfect surveillance cells. Impressively\, they are able to 
 promptly change their activation states in response to different neural re
 quirements making them also efficient responders of the brain. At the netw
 ork level\, glial cells communicate with each other by means of gap juncti
 onal coupling. Moreover\, they also have unique properties in different re
 gions of the brain suggesting their versatile and diverse functions. Indee
 d\, remarkable roles of astrocytes and microglia in synaptic development\,
  transmission\, plasticity and even learning and memory have been demonstr
 ated. Dysfunctions in glial cells have also been linked to a variety of pa
 thologies including neuroinflammation\, neurodegeneration as well as devel
 opmental disorders. Given the complexity of the brain in physiology and pa
 thology\, it is intuitive that neurons and glia exist and operate together
  in well-defined and regulated manner. Therefore\, to better understand th
 eir properties and functions\, it is important to understand complementary
  mechanisms and how they may interact. Furthermore\, research on neurons a
 nd glia can largely benefit from each other in terms of technical advances
  and research tools. In this seminar\, I will give a brief introduction to
  neuroglia interactions and share with you some of my research experience 
 on neurons and glia using mainly electrophysiological and live-imaging tec
 hniques in the context of synaptic transmission\, development and patholog
 y.\n
LOCATION:Seminar Room\, Lab Building East\, ISTA
ORGANIZER:ddomniso@ist.ac.at
SUMMARY:Giselle Cheung-Johnson: Understanding brain functions from both neu
 ronal and glial perspectives
URL:https://talks-calendar.ista.ac.at/events/661
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