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CALSCALE:GREGORIAN
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TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20260329T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
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DTSTART:20251026T020000
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BEGIN:VEVENT
DTSTAMP:20260424T040558Z
UID:1771502400@ist.ac.at
DTSTART:20260219T130000
DTEND:20260219T140000
DESCRIPTION:Speaker: Ivana Matijevic\nAbstract: Understanding what sets the
  timing of cellular activation remains a central challenge in dynamic sign
 aling systems. Rab5 activation on membranes emerges from a feedback-drive
 n\, threshold-controlled process shaped by catalytic input\, substrate ava
 ilability\, and spatial confinement. Here\, we probe how spatial scale in
 teracts with inhibitory (GDI) and activating mechanisms (RR) to shape tem
 poral responses. By systematically varying these parameters\, we aim to b
 etter understand their roles and uncover how Rab5 activation emerges fro
 m coupled spatial and biochemical input. 
LOCATION:Central Bldg / O1 / Mondi 2a&b\, ISTA
ORGANIZER:rita.pacarada@ist.ac.at
SUMMARY:Ivana Matijevic: When Biochemistry Meets Geometry: Spatial and Bioc
 hemical Determinants of Rab5 Activation 
URL:https://talks-calendar.ista.ac.at/events/6285
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