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DTSTART:20260329T030000
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DTSTART:20251026T020000
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DTSTAMP:20260424T113924Z
UID:6870e6230f4e3012113121@ist.ac.at
DTSTART:20251113T110000
DTEND:20251113T120000
DESCRIPTION:Speaker: Weria Pezeshkian\nhosted by Andela Saric\nAbstract: Bi
 omembranes are integral part of the cell architecture. They are a two-dime
 nsional fluid\, composed of myriad proteins and lipid species\, which prov
 ide identity to the cell and to many internal organelles. An intriguing as
 pect of membranes is their ability to assume a variety of shapes\, which i
 s crucial for many cellular processes such as food update\, waste disposal
 \, energy generation and cell division. Uncovering the mechanisms that con
 trol biomembrane shapes are essential for understanding their function in 
 cells\, diseases and for many biotechnological purposes such as the ration
 al design of drug delivery vehicles and vaccine development.In this talk\,
  I will present our recent progress in developing multiscale computational
  frameworks to investigate the spatial organization of biomembranes. I wil
 l illustrate how these simulations uncover intricate molecular details and
  generate testable predictions that can complement experimental results. N
 ext\, I will highlight our latest findings\, including the emergence of no
 n-intuitive mechanical behaviors in membranes with high topological genus\
 , and the behaviours of active membranes (membranes containing enzymatic a
 ctive proteins). Finally\, I will discuss how close we are to simulating r
 ealistic cellular membranes and sketch a possible way ahead.
LOCATION:Central Bldg / O1 / Mondi 2a (I01.O1.008)\, ISTA
ORGANIZER:cpetz@ist.ac.at
SUMMARY:Weria Pezeshkian: Multiscale Simulation of Biomembranes: bridging t
 he gap between simple models and complex reality
URL:https://talks-calendar.ista.ac.at/events/6073
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