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DTSTAMP:20260424T143145Z
UID:1739178000@ist.ac.at
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DESCRIPTION:Speaker: Marwan Elkrewi\nhosted by Maximilian Jösch\nAbstract:
  In recent years\, large-scale genomics paved the way for the rapid identi
 fication of sex chromosomes in a large variety of species. Although this h
 as yielded new insights into sex chromosome evolution and its consequences
 \, evidence is still lacking for several of the proposed models. Artemia b
 rine shrimp\, crustaceans from the Branchiopoda class\, are well suited fo
 r testing our current models\, which are heavily biased towards XY systems
 . They have ZW sex chromosomes\, which are not well-characterized and the 
 sex determination mechanism is currently unknown. They also have closely r
 elated sexual and asexual species\, which makes them a great model for stu
 dying the genetic basis of parthenogenesis. For the first part of my PhD\,
  we generate chromosome-level assemblies for two Artemia species. We use t
 he assemblies to characterize the extent of conservation and differentiati
 on of the sex chromosomes across the clade\, and combine them with RNAseq 
 data to identify genes in the sex determination cascade. In the second par
 t\, we generate single-nucleus RNAseq of the Artemia female reproductive s
 ystem data to explore the expression patterns of the Z-specific region thr
 oughout meiosis. In the last part\, we use a combination of newly generate
 d single nucleus RNAseq and WGS data of an asexual species and a closely r
 elated sexual species to shed light on the molecular pathways involved in 
 the transition to asexual reproduction in Artemia.
LOCATION:Central Bldg / O1 / Ballroom (I01.O1.006) and Zoom\, ISTA
ORGANIZER:
SUMMARY:Marwan Elkrewi: Thesis Defense: Evolution of sex chromosomes\, sex 
 determination and asexuality in Artemia brine shrimp 
URL:https://talks-calendar.ista.ac.at/events/5558
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