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DTSTART:20150329T030000
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DTSTAMP:20260501T140124Z
UID:53ec671d8cce3385962120@ist.ac.at
DTSTART:20150427T163000
DTEND:20150427T173000
DESCRIPTION:Speaker: Jan Born\nAbstract: Whereas memories are encoded and r
 etrieved optimally when the brain is awake\, the consolidation of memory r
 equires an offline mode of processing as established optimally only during
  sleep. Recent studies have elucidated some of the neurophysiological mech
 anims underlying the consolidation of memories during sleep\, especially i
 n the hippocampus-dependent declarative memory system. This system is capa
 ble of rapidly forming an initial memory representation for an episode upo
 n its one-time occurrence\, and is thus at the basis of the formation of a
 ny long-term memory. Consolidation of hippocampus-dependent memories repre
 sents an active system consolidation process that takes place mainly durin
 g slow wave sleep (SWS) rather than REM sleep. It selectively strengthens 
 memories of future relevance and leads to a qualitative transformation of 
 the memory representation. System consolidation during sleep critically re
 lies on the neural reactivation of newly encoded memory representations in
  hippocampal circuitry\, which likely stimulate a gradual redistribution o
 f the representations towards extra-hippocampal\, mainly neocortical netwo
 rks serving as long-term store. Hippocampal memory reactivations are drive
 n by the <1Hz EEG slow oscillations that dominate SWS and are generated in
  neocortical networks partly as a function of the prior use of these netwo
 rks for encoding of information. By synchronizing hippocampocal memory rea
 ctivations with specific activity from other brain areas\, including thala
 mo-cortical spindles\, slow oscillations enable persisting plastic changes
  underlying the long-term storage of memories in the neocortex.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:aeller@ist.ac.at
SUMMARY:Jan Born: The Institute Colloquium: The memory function of sleep
URL:https://talks-calendar.ista.ac.at/events/538
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