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TZID:Europe/Vienna
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DTSTART:20150329T030000
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TZOFFSETTO:+0200
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DTSTART:20141026T020000
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BEGIN:VEVENT
DTSTAMP:20260501T201230Z
UID:500404511be72@ist.ac.at
DTSTART:20141124T163000
DTEND:20141124T173000
DESCRIPTION:Speaker: Matthieu Piel\nAbstract: In tissues\, cells have their
  physical space constrained by neighboring cells and extracellular matrix.
  In the recent years\, we have developed simple and versatile devices to p
 recisely and dynamically control this confinement parameter in cultured ce
 lls. I will present results we obtained on the effect of confinement on ce
 ll migration focusing on the main parameter limiting cell migration in con
 finement: the deformation of its nucleus. I will conclude presenting intru
 iguing results showing that large deformations of migrating cells induce s
 trong damages of their nucleus raising the question of how immune cells su
 ch as dendritic cells can combine high motility and long term survival.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Matthieu Piel: Institute Colloquium: Deforming the nucleus during c
 ell migration: mechanism\, consequ
URL:https://talks-calendar.ista.ac.at/events/528
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