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DTSTAMP:20260312T163104Z
UID:66deacb95599a972864375@ist.ac.at
DTSTART:20250122T110000
DTEND:20250122T120000
DESCRIPTION:Speaker: Kirsten Bomblies\nhosted by Filip Ruzicka (Vicoso grou
 p)\nAbstract: A large slice of evolution may be hidden to us\, involving a
 daptations to cellular challenges that are not obvious to the human viewer
  but are important for survival. A unique system for studying such challen
 ges is polyploidy\, which results from a dramatic mutation  whole genome d
 uplication. Genome duplication doubles the number of chromosomes\, which i
 s generally coupled with increased cell size\, and these changes have knoc
 k-on effects on the physiology of organisms. Some can play out as benefici
 al\, for example driving the stress tolerance polyploids are famous for\, 
 while others are challenges that necessitate evolutionary adjustment. We u
 se Arabidopsis arenosa\, which occurs naturally in both a diploid and an a
 utotetraploid form\, and where we can also make neo-autotetraploids from d
 iploids in the lab. This system allows us to study both the challenges tha
 t arise\, as well as the solutions that evolved in nature. Relying on geno
 me scans for selection we did on the natural tetraploid\, we have been fol
 lowing up candidate genes as well as discovering novel challenges employin
 g both forward and reverse adaptation genomics. I will discuss two set of 
 stories that highlight these two approaches and will discuss what we have 
 learned about how cellular processes can evolve to compensate for whole-sa
 le organismic changes.
LOCATION:Central Bldg / O1 / Mondi 2a (I01.O1.008)\, ISTA
ORGANIZER:fruzicka@ist.ac.at
SUMMARY:Kirsten Bomblies: Learning to tango with four – adaptation to 
 whole genome duplication
URL:https://talks-calendar.ista.ac.at/events/5225
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