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TZID:Europe/Vienna
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DTSTART:20140330T030000
TZOFFSETFROM:+0100
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DTSTART:20141026T020000
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BEGIN:VEVENT
DTSTAMP:20260502T050901Z
UID:50040450e2dc5@ist.ac.at
DTSTART:20140623T163000
DTEND:20140623T173000
DESCRIPTION:Speaker: Tom Muir\nAbstract: Inteins are auto-processing domain
 s found in organisms from all domains of life. These proteins are molecula
 r escape artists that spontaneously excise themselves in a traceless manne
 r from essentially any protein sequence in which they are inserted. Protei
 n chemists have exploited various facets of intein reactivity to modify pr
 oteins in myriad ways for both basic biological research as well as potent
 ial therapeutic applications. Here\, I discuss our recent insights into ho
 w inteins catalyze protein splicing and how this has led to the developmen
 t of new methods for the manipulation of protein structure in the test tub
 e and in cells. These applications will be highlighted through specific ap
 plications in the area of chromatin biology.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Tom Muir: Institute Colloquium: Houdini Proteins:  Discovery an
 d Applications of Ultrafast In
URL:https://talks-calendar.ista.ac.at/events/516
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