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DTSTART:20140330T030000
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DTSTART:20141026T020000
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DTSTAMP:20260502T051745Z
UID:50040450e0f91@ist.ac.at
DTSTART:20140616T163000
DTEND:20140616T173000
DESCRIPTION:Speaker: Magnus Nordborg\nAbstract: Plants display remarkable d
 evelopmental and genetic adaptation to their environment. It has long been
  postulated that epigenetics plays a key role in these processes\, but wit
 h few exceptions\, solid evidence is lacking. A key impediment to understa
 nding these processes is the lack of information on the extent of epigenet
 ic variation and how it relates to genetic and phenotypic variation. Here 
 we investigate DNA methylation variation in Swedish Arabidopsis thaliana a
 ccessions\, demonstrating that methylation of transposable elements is tem
 perature sensitive and associated with genetic polymorphism in both cis an
 d trans\, whereas gene body methylation is highly correlated with climate 
 of origin and associated with genetic polymorphism in trans that shows evi
 dence of local adaptation. While genome-wide surveys of naturally occurrin
 g DNA methylation have been published previously\, the degree of genetic c
 ontrol revealed here is unprecedented. Furthermore\, the observation that 
 DNA methylation is associated with climate\, and is apparently adaptively 
 important\, is completely novel. Our findings provide a basis for further 
 dissecting the molecular genetic basis of epigenetic variation\, and its r
 ole in adaptation.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Magnus Nordborg: Institute Colloquium: Exploring the genotype-pheno
 type map in Arabidopsis
URL:https://talks-calendar.ista.ac.at/events/515
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