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DTSTART:20140330T030000
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DTSTART:20131027T020000
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DTSTAMP:20260504T133948Z
UID:50040450ac24a@ist.ac.at
DTSTART:20131209T163000
DTEND:20131209T173000
DESCRIPTION:Speaker: Silvia Arber\nAbstract: Motor behavior represents the 
 ultimate output of most nervous system activity. Its accuracy\ndepends on 
 precise connectivity of many different circuit modules\, together controll
 ing programs\nfor motor output\, computing predicted action and monitoring
  consequences of past action. Body\nmovement entails the concerted activat
 ion of limb muscles innervated by specialized groups of\nspinal motor neur
 ons\, yet very little is known about synaptic organization and function of
 \nconnectivity modules to diverse motor neurons\, at the core of regulatin
 g motor output programs.\nThis talk will focus on our recent work unraveli
 ng organizational and functional principles of\nneuronal circuits regulati
 ng the control of spinal motor neurons innervating limb muscles.\nExploiti
 ng transsynaptic virus tools\, mouse genetics and behavioral experiments\,
  we found striking\ndifferences in anatomical and functional organization 
 of direct connections to different motor\nneuron pools by distinct classes
  of spinal interneurons and supraspinal brainstem nuclei. Our\nstudies on 
 organization and function of descending brainstem command lines point towa
 rds the\nexistence of segregated action maps to allow motor program divers
 ification at the level of the\nbrainstem\, just one synapse away from moto
 r neurons. Together\, our findings demonstrate that\nfunctional difference
 s discerned at the motor output level and important for appropriate motor\
 nbehavior are engraved anatomically and genetically as differential spatia
 l maps at the premotor\nlevel\, both at spinal and supraspinal levels
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Silvia Arber: The Institute Colloquium: The ups and downs of motor 
 circuit organization
URL:https://talks-calendar.ista.ac.at/events/499
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