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CALSCALE:GREGORIAN
METHOD:PUBLISH
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TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20130331T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
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BEGIN:STANDARD
DTSTART:20131027T020000
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BEGIN:VEVENT
DTSTAMP:20260504T235003Z
UID:50040450707eb@ist.ac.at
DTSTART:20130527T163000
DTEND:20130527T173000
DESCRIPTION:Speaker: Jack Taunton\nAbstract: Actin polymerization drives me
 mbrane movement and is spatially\nregulated by membrane-associated signali
 ng complexes. Rho-family\nGTPases (such as Rac and Cdc42) bind and activat
 e actin nucleation\nfactors\, which localize to discrete zones--- along th
 e membrane\ncorresponding to sites of actin polymerization and membrane\np
 rotrusions. However\, it is unclear how actin networks spatially organize\
 nsignaling proteins into clusters and how this spatial organization affect
 s\nsignal transduction. By reconstituting a Cdc42-driven signaling cascade
 \nfrom purified proteins and supported lipid bilayers\, we have gained\nme
 chanistic insights into how actin dynamics exert local feedback control\no
 n signal transduction events at the membrane.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Jack Taunton: The Institute Colloquium: Feedback Control of Signal 
 Transduction by Dynamic Actin Ne
URL:https://talks-calendar.ista.ac.at/events/485
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