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DTSTART:20130331T030000
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DTSTART:20121028T020000
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DTSTAMP:20260505T020629Z
UID:5004045051d3d@ist.ac.at
DTSTART:20130211T163000
DTEND:20130211T173000
DESCRIPTION:Speaker: Ruth Lehmann\nAbstract: Germ cells are the stem cells 
 of the next generation. They are not needed for any\nvital functions of an
  organism\, yet\, as sperm or egg\, they are key to reproduction.\nThus\, 
 due to their special needs\, we envision that these cells are endowed with
 \nspecialized mechanisms that control their behavior. We are particularly 
 interested\nin how the germ cell program is established in the early embry
 o and have found that\ntranscription is largely blocked in early germ cell
 s while specific maternal products\npersist longer in germ cells than in t
 he rest of the body. In order to produce gametes\nthroughout adult life ge
 rm cells regulate the rate of self- renewal and\ndifferentiation. We are i
 nterested in the control mechanisms that prevent\npremature differentiatio
 n and that detect and eliminate aberrant gametes. We\nstudy how germ cells
  defend against endogenous threats such as transposable\nelements while ke
 eping the opportunity for genetic change and evolution open.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Ruth Lehmann: The Institute Colloquium: Making and protecting the g
 ermline
URL:https://talks-calendar.ista.ac.at/events/475
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