BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20240331T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
END:DAYLIGHT
BEGIN:STANDARD
DTSTART:20231029T020000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10
TZNAME:CET
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20260404T075023Z
UID:1705590000@ist.ac.at
DTSTART:20240118T160000
DTEND:20240118T170000
DESCRIPTION:Speaker: Roland Tschismarov\, Head of Translational Research\nA
 bstract: AbstractWe at Loop Lab are dedicated to building what we call Sel
 f-Amplifying Biologics\, or SelfAmps\, novel virus-based based therapeutic
 s tailor-made for the treatment of various diseases. To this end\, we firs
 t identify a safe viral backbone suited to the indication at hand in terms
  of immunogenicity\, replication rate etc. We then exchange the original v
 iral surface receptors to modify tropism for tissue- or cell-type specific
  delivery\, introduce genetic information encoding a disease-specific payl
 oad as well as factors modulating local immunity. The SelfAmp is then surf
 ace modified during or after production\, for increased stability and cloa
 king from anti-drug responses. During the talk I would like to talk about
  how I ended up at Loop Lab and briefly discuss the stages of my academic 
 and industry career that led me here\, particularly focusing on the transi
 tion to the private sector and what my specific job roles actually entaile
 d. About the speaker:Roland Tschismarov is an immunologist with a strong 
 interest in T cell biology and host pathogen interaction. He obtained his 
 PhD from the Medical University Vienna\, primarily working on epigenetic r
 egulation of T cell development and function\, before joining Max Perutz L
 abs Vienna as a university assistant/postdoc\, focusing on pattern recogni
 tion and immune responses to pathogens. He joined Themis Bioscience in 201
 8\, supporting clinical study design\, conduct and analysis. After the com
 pany's acquisition by MSD in 2020 he was employed as a Principal Scientist
  working on preclinical development and regulatory interactions. He co-fou
 nded Loop Lab Bio in 2023 and currently acts as head of translational rese
 arch\, leading a team of scientists dedicated to bringing the company's vi
 sion of novel virus-based medicines into animal models and\, ultimately\, 
 humans.
LOCATION:Down Town\, Central Building\, ISTA
ORGANIZER:Edmundo.Sanchez@ist.ac.at
SUMMARY:Roland Tschismarov\, Head of Translational Research: xista talk | R
 oland Tschismarov\, Loop Lab Bio
URL:https://talks-calendar.ista.ac.at/events/4730
END:VEVENT
END:VCALENDAR