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TZID:Europe/Vienna
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DTSTART:20130331T030000
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DTSTART:20121028T020000
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BEGIN:VEVENT
DTSTAMP:20260505T043340Z
UID:5004044c9caec@ist.ac.at
DTSTART:20121126T163000
DTEND:20121126T173000
DESCRIPTION:Speaker: Erin Schuman\nAbstract: Neurogliaform cells are unique
  components in microcircuits of the cerebral cortex being capable of elici
 ting\nslow inhibition. These neurons reach GABAA and GABAB receptors on ta
 rget cells through a novel form of\nsingle cell driven volume transmission
  by flooding the area covered by the extremely dense axonal\narborisation 
 with GABA\, thus extend the boundaries of classical unitary (single cell t
 riggered) signals\ntowards network events. We developed a combination of o
 ligocellular gene-chip and single cell digital PCR\nmethods in order to an
 alyze the global gene expression profile of physiologically and anatomical
 ly\nidentified neurogliaform cells. This resulted in the functional identi
 fication of several unexpected marker\ngenes with previously unknown funct
 ions in the cortical microcircuit. The presentation will also discuss the\
 nhypothesis that neurogliaform cells would act on all cellular elements of
  the cortex including parts of\nneurons not accessible for synapses\, glia
 l cells and the vasculature in the area covered with GABA and/or\ncotransm
 itters released by neurogliaform cells.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Erin Schuman: The Institute Colloquium: Local Protein Synthesis in 
 Neurons
URL:https://talks-calendar.ista.ac.at/events/469
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