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DTSTART:20120325T030000
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DTSTAMP:20260505T161400Z
UID:5004044ce284b@ist.ac.at
DTSTART:20120416T163000
DTEND:20120416T173000
DESCRIPTION:Speaker: Nikos K. Logothetis\nAbstract: Neuroanatomical cortico
 -cortical and cortico-subcortical connections have been examined mainly\nb
 y means of degeneration methods and anterograde and retrograde tracer tech
 niques. Although\nsuch studies have demonstrated the value of the informat
 ion gained from the investigation of the\ntopographic connections between 
 different brain areas\, they do require fixed\, processed tissue for\ndata
  analysis and therefore cannot be applied to animals participating in long
 itudinal studies.\nCapacities such as plasticity and learning are indeed b
 est studied with non-destructive techniques\nthat can be applied repeatedl
 y and\, ideally\, combined with neuroimaging or electrophysiology\nstudies
 .\nThe recent development of MR-visible tracers that can be infused into a
  specific brain region and\nare transported anterogradely transsynapticall
 y is one such technique. Simultaneous electrical\nstimulation (ES) and fMR
 I (esfMRI) is another. In fact\, esfMRI offers a unique opportunity for\nv
 isualizing the networks underlying electrostimulation-induced behaviors\, 
 to map the\nneuromodulatory systems\, or to study the effects of regional 
 synaptic plasticity\, e.g. LTP in\nhippocampus\, on cortical connectivity.
  In my talk I’ll present new data on MR-visible tracers and\nesfMRI that 
 show the capacity of these methods for the study of the organization of co
 rtical\nmicrocircuits and effective connectivity. I shall also show first 
 results from studies mapping\nnetwork topologies by triggering imaging at 
 structure-specific events\, e.g. hippocampal ripples or\ncross-frequency c
 oupling events.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Nikos K. Logothetis: Institute Colloquium: In vivo Connectivity: Pa
 ramagnetic Tracers\, Electrical Stimulat
URL:https://talks-calendar.ista.ac.at/events/453
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