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DTSTAMP:20260424T143118Z
UID:1707129000@ist.ac.at
DTSTART:20240205T113000
DTEND:20240205T123000
DESCRIPTION:Speaker: Nicolas Tapon & Guillaume Salbreux\nhosted by Anna Kic
 heva\nAbstract: How do cells in a developing organism stop growing and div
 iding when the correct body size has been reached? During development\, m
 ulticellular organisms undergo stereotypical patterns of tissue growth in 
 space and time\, but how this is orchestrated remains unclear. Understandi
 ng these fundamental biological processes has clear implications for cance
 r\, where cells lose the ability to respond to tissue size boundaries\, an
 d for regenerative medicine\, where the proliferative potential of quiesce
 nt cells must be unleashed in a controlled manner. We are a collaborative 
 team of developmental biologists (Tapon) and theoretical physicists (Salbr
 eux) who combine quantitative biology and theoretical approaches to study 
 developmental growth control in the Drosophila abdominal epidermis. This
  tissue is highly suited to long-term live-imaging and therefore allows us
  to directly observe the kinetics of tissue growth in the living animal\, 
 as well as interfere with this process using genetics and laser ablations.
  We will present our latest findings on how cells coordinate their cell cy
 cles during abdomen development and how we use perturbations to unravel th
 e signals that promote the timely termination developmental growth.
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:maria.arias.sutil@ista.ac.at
SUMMARY:Nicolas Tapon & Guillaume Salbreux: How big is big enough? Unravell
 ing the developmental control of tissue growth in the fly abdomen 
URL:https://talks-calendar.ista.ac.at/events/4465
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