BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20120325T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
END:DAYLIGHT
BEGIN:STANDARD
DTSTART:20111030T020000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10
TZNAME:CET
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20260506T033550Z
UID:5004044d25e56@ist.ac.at
DTSTART:20111212T163000
DTEND:20111212T173000
DESCRIPTION:Speaker: Lance Davidson\nAbstract: Embryonic shape and form is 
 driven by the physical mechanics of component cells\nand tissues. Genes an
 d signaling networks may control the protein composition of\ncells but it 
 is the forces generated by cells and their interactions with their\nsurrou
 ndings that dictate the form of the resulting embryo and the survival of t
 he\nlarva. We are applying basic principles of experimental biophysics and
 \ndevelopmental biology to investigate the roles of such forces and tissue
 \nbiomechanics in early development. Our first efforts have revealed crypt
 ic changes\nin biomechanical properties of developing amphibian embryos an
 d the\nspatiotemporal variation of these properties at the cellular and or
 ganismal scale.\nUsing molecular perturbations we have begun a systematic 
 analysis of the roles of\ncell- and tissue-structural proteins in establis
 hing "passive" material properties and\n"active" force-generating programs
  in key tissues that drive embryos from spherical\nballs of cells to elong
 ate tadpoles. Interestingly\, tissues at the earliest stages of\nembryonic
  development are ultra-soft (< 100 Pa) and are shaped principally by the\n
 action of the actomyosin cytoskeleton. We will discuss how observations fr
 om these\nstudies are driving development of new theories of morphogenesis
  incorporating\nboth cell signaling and mechanical feedback and the develo
 pment of new\nexperimental tools to test them.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Lance Davidson: Institute Colloquium: Reverse engineering the physi
 cal mechanics of embryonic morphog
URL:https://talks-calendar.ista.ac.at/events/443
END:VEVENT
END:VCALENDAR