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TZID:Europe/Vienna
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DTSTART:20230326T030000
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DTSTAMP:20260424T143006Z
UID:64c3afe647d44136108149@ist.ac.at
DTSTART:20230821T140000
DTEND:20230821T150000
DESCRIPTION:Speaker: Matthew Banghart\nhosted by Maximilian Jösch\nAbstrac
 t: Pain perception is heavily shaped by cognitive process and pharmacologi
 cal drugs. In this talk\, I will present data obtained in mice supporting 
 the view that the neural circuit mechanisms that underlie placebo antinoci
 ception and morphine antinociception converge on the midbrain periaqueduct
 al gray. Our results point to a role for descending cortical projections i
 n placebo\, but not morphine antinociception. I will also discuss our work
  developing a photopharmacological toolkit for bidirectional regulation of
  endogenous opioid receptors in vivo using light\, and how we are using th
 ese tools to uncover the role of endogenous opioid peptide signaling in pl
 acebo antinociception. Collectively\, this work illuminates neural pathway
 s that contribute to cognitive and pharmacological pain modulation and pav
 es the way for spatiotemporally precise behavioral photopharmacology exper
 iments in model organisms.
LOCATION:Office Bldg West / Ground floor / Heinzel Seminar Room (I21.EG.101
 )\, ISTA
ORGANIZER:mmosiash@ist.ac.at
SUMMARY:Matthew Banghart: Top-down control of descending pain modulation vi
 a the periaqueductal gray
URL:https://talks-calendar.ista.ac.at/events/4352
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