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DTSTAMP:20260405T232542Z
UID:1695132000@ist.ac.at
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DESCRIPTION:Speaker: Alessandro Venturino\nAbstract: Mental health disorder
 s\, like depression\, are one of the biggest challenges of modern society.
  Since 2019\, in USA and EU\, the prevalence of depression has risen by 28
 % and approximately 70 million people receive antidepressants every year. 
 Traditional antidepressants cause severe side effects and more than 30% of
  the patients fail to achieve remission. Ketamine is a very effective drug
  for the treatment of depression\, but\, given the high short and longterm
  dissociative effects\, can be administered to a limited group of patients
 . The Siegert group discovered that repeated ketamine exposure promotes ex
 tracellular matrix remodeling and juvenilelike plasticity induction. Inter
 estingly\, the exposure to pulsed light at 60 Hz recapitulates the pharmac
 ological effect of ketamine non-invasively (Venturino et al.\, Cell Report
 s 2021). Further behavioral data showed that 60 Hz light entrainment was a
 ble to promote learning and memory and rescue social interaction in precli
 nical models of depression. Based on this discovery we founded Syntropic M
 edical\, an ISTA spin-off company that aims to create the first medical de
 vice for the non-invasive treatment of depression. Syntropic Medical is a 
 dynamic and fast-growing startup company founded by Alessandro Venturino\,
  Sandra Siegert\, and Mark Caffrey. Syntropic has completed the preclinica
 l testing\, and it’s now actively preparing for clinical trials for FDA 
 approval. Syntropic recently received the AWS Seed funding grant.
LOCATION:Down Town\, ISTA
ORGANIZER:
SUMMARY:Alessandro Venturino: The New Standard In Drug-Free Mental Health T
 herapy
URL:https://talks-calendar.ista.ac.at/events/4349
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