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DTSTART:20110327T030000
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BEGIN:VEVENT
DTSTAMP:20260515T162246Z
UID:5004044d765e1@ist.ac.at
DTSTART:20110328T154500
DTEND:20110328T170000
DESCRIPTION:Speaker: Matthew Larkum\nAbstract: The neocortex and its intera
 ction with the thalamus lie at the heart of what makes mammals\nintelligen
 t. The neocortex is particularly adept at making associations and predicti
 ons about the\nworld. But how does the cortex achieve this? Although this 
 is an enormous question\, per se\, it is\nhighly probable that the answer 
 depends at least in part on the architecture of the cortex itself –\nboth
  in terms of the individual elements and their connectivity. Surprisingly\
 , treatment of the\nformer (understanding the intrinsic properties of neur
 ons) is still a largely open question and is\nrarely posed in relation to 
 the latter (the functional connectivity of the cortex). Since the cortex i
 s\npredominantly made up of pyramidal neurons\, it would appear absolutely
  fundamental to\nunderstand synaptic integration in these neurons in the c
 ontext of the network in which they are\nembedded.\nComputational theories
  of the cortex typical assume that the individual elements of the network\
 ,\nthe neurons\, are relatively simple in operation. They are normally rep
 resented as devices that sum\nthe total inputs arriving in a given time an
 d emit a binary output signal when the threshold\nnumber is reached. Here\
 , I will show that the major cortical element\, the pyramidal neuron\, is 
 far\nmore complex. I will present a hypothesis that the complexity of thes
 e neurons is fundamental to\nthe operation of the network. In practice\, m
 ost of the complexity of the neuron\, from the\ninput/output perspective\,
  lies in the active properties of the dendritic tree. This is particularly
  the\ncase in cortical pyramidal neurons. The general hypothesis therefore
  is that the specific properties\nand morphology of pyramidal cell dendrit
 es is inextricably linked to the architecture and function\nof the cortex.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:ihetzenauer@ist.ac.at
SUMMARY:Matthew Larkum: The contribution of single neurons to computation i
 n the cortical network
URL:https://talks-calendar.ista.ac.at/events/424
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