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DTSTART:20230326T030000
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DTSTART:20221030T020000
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BEGIN:VEVENT
DTSTAMP:20260425T051655Z
UID:1678201200@ist.ac.at
DTSTART:20230307T160000
DTEND:20230307T170000
DESCRIPTION:Speaker: Marlene Bartos\nhosted by Ryuichi Shigemoto\nAbstract:
  Title: Dentate gyrus circuits for encoding\, retrieval and discriminatio
 n of memoriesAbstractEncoding\, storing and recalling distinct memories of
  often-similar content are essential brain functions that play a key role 
 in guiding our daily behavior and decision-making. My groups’ efforts ar
 e to understand how this challenge is resolved in the dentate gyrus (DG)\,
  a brain area involved in several mnemonic functions. As the initial stage
  of the trisynaptic hippocampal circuit\, DG granule cells (GCs) encode sp
 ace and context by location-dependent discharges\, forming a cognitive map
  of an experienced environment. In this talk\, I will address (1) how spat
 ial maps emerge in the DG during learning by performing 2-Photon calcium i
 maging of neuronal activity in head-fixed mice navigating through virtual 
 realities. (2) I will address how GABAergic inhibitory interneurons may co
 ntribute to the high stability of spatial maps and discrimination among di
 fferent spatial maps. (3) Finally\, I will highlight the relationship betw
 een the information about space and context carried by the activity of med
 ial entorhinal cortex (MEC) inputs are translated in a code carried by act
 ive DG GC populations. Thus\, we aim to shed light on how information is r
 outed from MEC inputs through the DG to downstream hippocampal subfields t
 o support cognitive demands.
LOCATION:Mondi 2\, ISTA
ORGANIZER:mariam.mosiashvili@ist.ac.at
SUMMARY:Marlene Bartos: NDT\, Marlene Bartos 
URL:https://talks-calendar.ista.ac.at/events/4057
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