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UID:1678809600@ist.ac.at
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DESCRIPTION:Speaker: Gyorgy Buzsaki\nhosted by Jozsef Csicsvari\nAbstract: 
 Please note that registration for this event is now closed.  This talk wi
 ll be recorded and uploaded to our YouTube channel (https://www.youtube.co
 m/user/ISTAustria) within the upcoming week.AbstractCurrent neuroscience i
 s largely fueled by an empiricist philosophy that assumes the brain’s go
 al is to perceive\, represent the world\, and learn the truth. An inevitab
 le consequence of this framework is the assumption of a decision-making ho
 munculus wedged between our perception and actions. In contrast\, I advoca
 te that the brain’s fundamental function is to induce actions and predic
 t the consequences of those actions to support the survival and prosperity
  of the brain’s host. Only actions can provide a second opinion about th
 e relevance of the sensory inputs and provide meaning for and interpretati
 on of those inputs. In this “inside-out” framework\, the brain comes w
 ith a preconfigured and self-organized dynamic that constrains how it acts
  and views the world. In the brain’s nonegalitarian organization\, preex
 isting nonsense brain patterns become meaningful through action-based expe
 rience. I will show recent experiments that support this framework and ill
 ustrate how seemingly disparate neural computations\, such as metabolic ho
 meostasis/allostasis and memory-guided behaviors\, have co-evolved at ever
 y step within the same brain circuits.Buzsaki\, G. Rhythms of the Brain (O
 UP 2006)Buzsaki G. The Brain from Inside Out (OUP 2019)Buzsaki G. How the 
 Brain ‘Constructs’ the Outside World. Scientific American\, April 2022
 . https://www.scientificamerican.com/article/how-the-brain-constructs-the-
 outside-world/BioGyörgy Buzsáki identified a hierarchical organization o
 f brain oscillations and proposed how these rhythms support a 'brain synta
 x’\, a physiological basis of cognitive operations. His work changed how
  we think about information encoding in the healthy and diseased brain\, s
 uch as epilepsy and psychiatric diseases. His most influential work is kno
 wn as the two-stage model of memory trace consolidation\, with hippocampal
  sharp wave ripples serving as a transfer mechanism from hippocampus to ne
 ocortex. Several laboratories worldwide have adopted his framework and pro
 vided supporting evidence for the two-stage model of memory in both experi
 mental animals and human subjects. Over the years\, the ‘ripple’ patte
 rn has become a quantifiable biomarker of cognition. Relevant to clinical 
 translation\, hippocampal ripples\, along with other brain rhythms that hi
 s laboratory has identified\, lend themselves to diagnosis of disease and 
 drug discovery.Buzsáki is Biggs Professor of Neuroscience at New York Uni
 versity. He is among the top 0.1% most-cited neuroscientists\, member of t
 he National Academy of Sciences USA\, \, member of Academia Europaea (http
 ://www.ae-info.org/ae/Acad_Main/Sections/Physiology_medicine/Physiology_me
 dicine_Members?pagenr=45) and the Hungarian Academy of Sciences. He sits o
 n the editorial boards of several leading neuroscience journals\, includin
 g Science and Neuron. He is a co-recipient of the 2011 Brain Prize and the
  winner of the Ralph W. Gerard Prize (2020\; SFN’s highest honor)\, The 
 Goldman-Rakic Prize (https://www.bbrfoundation.org/grants-prizes/prizes-aw
 ards/goldman-rakic-prize-outstanding-achievement-cognitive-neuroscience) (
 2021)\, The Ariëns Kappers Medal (http://en.wikipedia.org/wiki/Ari%C3%ABn
 s_Kappers_Medal) (Royal Netherlands Academy of Arts and Sciences)\, 2014\;
  Krieg Cortical Discoverer Award (http://cajalclub.org/id21.html) from the
  American Association of Anatomists (2001).Books: Rhythms of the Brain (OU
 P)\, 2006\; The Brain from Inside Out (OUP)\, 2019.
LOCATION:Raiffeisen Lecture Hall\, ISTA
ORGANIZER:arinya.eller@ist.ac.at
SUMMARY:Gyorgy Buzsaki: Ways to think about the brain: Emergence of cogniti
 on from action
URL:https://talks-calendar.ista.ac.at/events/3732
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