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DTSTART:20220327T030000
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DTSTAMP:20260404T035155Z
UID:612f3252ab316602736380@ist.ac.at
DTSTART:20220406T123000
DTEND:20220406T133000
DESCRIPTION:Speaker: Rahul Pisupati\nhosted by Nick Barton\nAbstract: The p
 ossibility that stable\, inherited\, epigenetic variation could play an im
 portant role in plant adaptation has been around for decades. Recent studi
 es in natural inbred lines of Arabidopsis thaliana showed that DNA methyla
 tion\, an epigenetic mark\, patterns are correlated with the climate of or
 igin of the lines. DNA methylation could be important for plant adaptation
  in theory\, but inference is confounded with underlying genetic variation
  driving methylation patterns. We do not fully understand the underlying c
 auses of these correlations. Here we dissect the effects of genotype\, env
 ironment and epigenetic inheritance on DNA methylation\, by looking at the
  intercross populations. We confirmed the stable inheritance of DNA methyl
 ation marks and estimated epimutation rates. Additionally\, we identified 
 novel trans- regulators for DNA methylation using QTL mapping. These resul
 ts suggest DNA methylation might indeed be important for plant adaptation\
 , but is a part of genetic mechanism.
LOCATION:I22 Lakeside View (I22.O1.006)\, ISTA
ORGANIZER:apal@ist.ac.at
SUMMARY:Rahul Pisupati: Genetics of epigenetics in Arabidopsis thaliana
URL:https://talks-calendar.ista.ac.at/events/3596
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