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DTSTAMP:20260405T062604Z
UID:61691ed053c52153195356@ist.ac.at
DTSTART:20220317T110000
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DESCRIPTION:Speaker: Valerio Sorichetti\nhosted by Andela Saric\nAbstract: 
 The problem of irreversible polymerization is fundamental for its many app
 lications to different fields\, from material science to biology. In livin
 g cells\, cytoskeletal filaments grow and bundle together\, forming comple
 x networks. Since the assembly and bundling of these filaments often invol
 ve energies of the order of hundreds or thousands of kT\, the final struct
 ure of the network will be heavily influenced by the kinetics of these pro
 cesses (Kayser et al.\, Soft Matter\, 2012\, 8\, 8873). Approaches based o
 n equilibrium physics are therefore bound to fail when studying the struct
 ural and mechanical properties of such networks\, and approaches that expl
 icitly considers the kinetics are necessary.We extend a previously develop
 ed theoretical framework (De Gennes\, J. Chem. Phys.\, 1982\, 76\, 3316) t
 o study how the average length L of a system of semiflexible filaments tha
 t anneal irreversibly via end-to-end reactions increases with time time. W
 e find that filament assembly is controlled by the short-time transversal 
 fluctuations\, which lead to a linear growth of L with time. We perform th
 e same calculations also for perfectly rigid rods\, which have no transver
 sal fluctuations modes\, showing that in this case L increases only as the
  square root of time. Finally\, we compare our theoretical predictions wit
 h molecular dynamics simulations of particles that aggregate irreversibly 
 into semiflexible filaments with a tunable persistence length\, finding an
  excellent agreement with the theoretical predictions.
LOCATION:Heinzel Seminar Room / Office Bldg West (I21.EG.101)\, ISTA
ORGANIZER:cpetz@ist.ac.at
SUMMARY:Valerio Sorichetti: Transversal fluctuations determine fast assembl
 y of semiflexible filaments
URL:https://talks-calendar.ista.ac.at/events/3570
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