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BEGIN:VEVENT
DTSTAMP:20260406T042012Z
UID:61efb66e6afa6356776784@ist.ac.at
DTSTART:20220201T100000
DTEND:20220201T111500
DESCRIPTION:Speaker: Jean-Francois Joanny\nhosted by Edouard Hannezo\nAbstr
 act: Mechanics and geometry of growing tissuesThe mechanical properties of
  biological tissues  are generally studied either at a macroscopic level b
 y considering the tissue as a liquid (with a non-conserved number of cells
 ) or at a microscopic cellular level by a vertex model that considers the 
 tissue as an evolving graph. We derive a covariant coarse-grained continuu
 m model of a generalized 2 dimensional vertex model of epithelial tissues.
  The formulation describes tissues with different underlying geometries\, 
 and allows for analytical description of the macroscopic behavior starting
  from the microscopic discrete vertex  model. Using a geometrical approach
  and out-of-equilibrium statistical mechanics\, we calculate various mecha
 nical properties of a tissue\, and their dependence on different variables
 \, including activity\, and disorder. Both plastic cellular rearrangements
  and the  elastic response\,  depend on the existence of mechanical residu
 al stresses at a cellular level. Our main result is an explicit calculatio
 n of the cell pressure in a homeosatic state.  Additionally\, we show that
  the homeostatic pressure can be negative and due to the existence of mech
 anical residual stresses. Using this geometric model we can readily distin
 ct between elasticity and plasticity in a growing\, flowing\, tissue.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:channezo@ist.ac.at
SUMMARY:Jean-Francois Joanny: Seminar - Jean-Francois Joanny
URL:https://talks-calendar.ista.ac.at/events/3502
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