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DTSTART:20210328T030000
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DTSTAMP:20260404T052223Z
UID:60f69bea32fc4310253847@ist.ac.at
DTSTART:20210730T110000
DTEND:20210730T120000
DESCRIPTION:Speaker: Jean-Leon Maitre\nhosted by Carl-Philipp Heisenberg\nA
 bstract: During pre-implantation development\, the mammalian embryo forms 
 the blastocyst. The architecture of the blastocyst is essential to the spe
 cification of the first mammalian lineages and to the implantation of the 
 embryo. Consisting of an epithelium enveloping a fluid-filled lumen and th
 e inner cell mass\, the blastocyst is sculpted by a succession of morphoge
 netic events. These deformations result from the changes in the forces and
  mechanical properties of the tissue composing the embryo. Combining micro
 scopy\, image analysis\, biophysical tools and genetics\, we study the mec
 hanical and cellular changes leading to the formation of the blastocyst. I
 n particular\, we uncovered how pulsatile contractility compacts the mouse
  embryo\, how asymmetric division of contractile domains couples cell posi
 tioning and specification\, and how hydraulic fracturing and active coarse
 ning position the lumen of the mouse blastocyst.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:amally@ist.ac.at
SUMMARY:Jean-Leon Maitre: Mechanics of blastocyst morphogenesis
URL:https://talks-calendar.ista.ac.at/events/3243
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