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DTSTAMP:20260427T194941Z
UID:577e0fb61c0a6936652765@ist.ac.at
DTSTART:20171120T160000
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DESCRIPTION:Speaker: David Schneider\nhosted by Sylvia Cremer\nAbstract: My
  group studies resilience to infections. We want to understand the elastic
 ity of the physiological response to infection and take two sorts of measu
 rements to do this.  First\, we want to understand how far physiology wil
 l stretch when faced with series of different doses of stressors.  We cal
 l this “disease tolerance” when the stressor is microbe load\, and “
 resilience” when we are speaking more generally.  Second\, we want to u
 nderstand how far we can stretch our physiology until it snaps\, leading t
 o a chronic condition or death. We mainly work on two systems.  First\, w
 e study fruit flies infected with bacteria\, fungi\, and viruses.  This l
 ets us use large numbers of animals to test our models.  We also study mi
 ce suffering from a model malaria caused by Plasmodium chabaudi.  Here we
  are looking at the circulating immune cells\, cytokines and metabolome as
  well as gross physiological markers to finely map the progression and res
 olution of the disease.  Our overarching goal is to come up with simple a
 nd inexpensive methods of improving outcomes from all infections\, without
  necessarily changing the rate we clear pathogens. 
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:kzaruba@ist.ac.at
SUMMARY:David Schneider: Defining the resilience of hosts to infections
URL:https://talks-calendar.ista.ac.at/events/32
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