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DTSTART:20180325T030000
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DTSTART:20171029T020000
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DTSTAMP:20260427T143527Z
UID:577e0eda99d32710497451@ist.ac.at
DTSTART:20171113T160000
DTEND:20171113T170000
DESCRIPTION:Speaker: Kenneth Birnbaum\nhosted by Eva Benkova\nAbstract: Pla
 nts are particularly adept at regeneration\, with the ability of most plan
 t taxa to replace lost or damaged adult organs by reassembling their adult
  growth centers known as meristems. The overall question my lab addresses 
 is what makes plant so good at regeneration? Or\, in more developmental te
 rms\, how does the plant replace lost cell identities and repattern the me
 ristem? The phenomenon of regeneration has helped shed light on the questi
 on of what exactly is a stem cell in plants and how is the plant meristem 
 is assembled during development. We use the Arabidopsis root as a model fo
 r plant regeneration with ability to live image regeneration\, employ sing
 le cell RNA-seq on regenerating cells\, and test models with genetic pertu
 rbation. Using these techniques\, our current model suggests that the firs
 t step in regeneration is not necessarily the activation of stem cells but
  rather the assembly of mature tissues. We found that regeneration resembl
 es embryogenesis or perhaps more broadly involves a signaling cassette inv
 olving cross between the hormones auxin and cytokinin that generates the b
 asic organization of the root. Cell types organize around this tissue “s
 caffold” and stem cells are eventually recruited from many different exi
 sting cells that essentially wind up on the right place. Stem cell behavio
 r only emerges after tissue assembly. Our current model is that the tissue
  composition and mechanical properties of the meristem together lead to st
 em cell identity. In this view\, the plant’s regenerative capacity arise
 s from the ability to restart tissue patterning on many different types of
  dividing cells where almost any dividing cell is fully capable of adoptin
 g stem cell activity.
LOCATION:Raiffeisen Lecture Hall\, Central Building\, ISTA
ORGANIZER:kzaruba@ist.ac.at
SUMMARY:Kenneth Birnbaum: From insult to organization: Regeneration of the 
 plant root meristem
URL:https://talks-calendar.ista.ac.at/events/31
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