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DTSTART:20210328T030000
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DTSTAMP:20260407T051609Z
UID:1619445600@ist.ac.at
DTSTART:20210426T160000
DTEND:20210426T170000
DESCRIPTION:Speaker: Irene Miguel-Aliaga\nhosted by Simon Hippenmeyer\nAbst
 ract: We are interested in the plasticity of adult organs: how and why org
 ans that we commonly regard as fully developed change in size and/or funct
 ion in response to environmental or internal challenges. We mainly use the
  Drosophila intestine and its neurons because they allow us to explore org
 an plasticity from an integrated perspective. We investigate how an organ 
 senses its internal milieu and the environment (e.g. nutrients\, microbiot
 a)\, how its adult progenitors respond by either maintaining or resizing t
 he organ\, and how its different cell types (epithelial\, muscle\, neural)
  communicate to achieve coordinated\, organ-level remodelling. I will pres
 ent some of our recent work\, which has uncovered unexpected sexual dimorp
 hisms\, as well as intestinal contributions to food intake and reproductiv
 e success. Intriguingly\, the intestine’s three-dimensional arrangement 
 within the body cavity may be relevant to how it communicates with other o
 rgans. I may also discuss our ongoing attempts to explore how broadly appl
 icable our findings might be using mouse and human models.
LOCATION:Online\, ISTA
ORGANIZER:arinya.eller@ist.ac.at
SUMMARY:Irene Miguel-Aliaga: Hungry brains and clever guts
URL:https://talks-calendar.ista.ac.at/events/2989
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