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DTSTART:20200329T030000
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BEGIN:VEVENT
DTSTAMP:20260406T042350Z
UID:1601038800@ist.ac.at
DTSTART:20200925T150000
DTEND:20200925T160000
DESCRIPTION:Speaker: Henning Sprekeler\nhosted by Tim Vogels\nAbstract: Inh
 ibitory interneurons come in different classes and form intricate circuits
 . While our knowledge of these circuits has advanced substantially over th
 e last decades\, it is not fully understood how the structure of these cir
 cuits relates to their function. I will present some of our recent attempt
 s to “understand” the structure of interneuron circuits by means of co
 mputational modeling. Surprisingly (at least for us)\, we found that promi
 nent features of inhibitory circuitry can be accounted for by an optimisat
 ion for excitation-inhibition (E/I) balance. In particular\, we find that 
 such an optimisation generates networks that resemble mouse V1 in terms of
  the structure of synaptic efficacies between principal cells and parvalbu
 min-positive interneurons. Moreover\, an optimisation for E/I balance acro
 ss neuronal compartments promotes a functional diversification of interneu
 rons into two classes that resemble parvalbumin and somatostatin-positive 
 interneurons. Time permitting\, I may briefly touch on recent work in whic
 h we link E/I balance to prediction error coding in V1. (Henning Sprekele
 r for Owen Mackwood\, Laura Bella Naumann\, Joram Keijser & Loreen Hertäg
 )
LOCATION:Online\, ISTA
ORGANIZER:
SUMMARY:Henning Sprekeler: Neuroscience Talk Henning Sprekeler
URL:https://talks-calendar.ista.ac.at/events/2870
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