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DTSTART:20200329T030000
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DTSTART:20191027T020000
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DTSTAMP:20260406T173333Z
UID:5e201a7323e1f804828930@ist.ac.at
DTSTART:20200210T100000
DTEND:20200210T110000
DESCRIPTION:Speaker: Arpiar Saunders\nhosted by Mario deBono\nAbstract: My 
 aim in research is to describe the cellular organization of the brain in s
 ystematic and scalable ways that inspire inductive hypotheses for how neur
 al circuits assemble\, support behavior and change during disease. My appr
 oach is to develop and then deploy new molecular technologies that allow q
 uantitative\, high-information-content descriptions of individual cells an
 d their synaptic connections. My seminar will introduce how single-cell ge
 nomic analysis can be used to 1) enable insights into mouse neural cell ty
 pes and their molecular programs\; 2) compare the cellular properties of n
 eural circuits across species and human genotypes\; and 3) create larger e
 xperimental systems that enable high-throughput reconstruction of cell-typ
 e-specific synaptic connectivity relationships. Such technologies should a
 llow wholly new (even currently unimaginable) ideas about brain function t
 o be conceived and tested\, supporting a transformation akin to the one th
 at arose in genetics as datasets expanded from genes to thousands of genom
 es.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:tguggenb@ist.ac.at
SUMMARY:Arpiar Saunders: High-throughput inference of brain composition and
  connectivity using single-cell genomics
URL:https://talks-calendar.ista.ac.at/events/2603
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