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DTSTART:20170326T030000
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DTSTART:20161030T020000
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DTSTAMP:20260429T024211Z
UID:586cfa046cddb520368216@ist.ac.at
DTSTART:20170131T094500
DTEND:20170131T104500
DESCRIPTION:Speaker: David A. DiGregorio\nAbstract: The efficiency\, precis
 ion and plasticity of communication at synapses is diverse throughout the 
 brain\, yet fundamental to processing and directing information that under
 lies behavior. In my laboratory we are in search of the fundamental biolog
 ical rules by which the diversity of synaptic function contributes to the 
 neural representation of the external and internal sensory world. Multi-se
 nsory integration within single neurons is thought to ensure reliable dete
 ction of external events. The cerebellar cortex is responsible for integra
 ting multiple sensory modalities in order to encode complex sensory featur
 es such as: unexpected motion\, linear acceleration\, and predictive error
 s of motor movements. Nevertheless\, surprisingly little is known about ho
 w the cerebellar cortex builds upon its well-known synaptic and cellular p
 roperties in order to dynamically integrate and process sensory informatio
 n. I will show how we combined input pathway-specific fluorescent labeling
 \, two-photon imaging and biophysical analysis of synaptic transmission (i
 n situ and in vivo)\, to examine how synaptic diversity contributes to the
  temporal coding of multisensory information in the cerebellar cortex. I w
 ill also show data supporting various cellular mechanisms that neurons emp
 loy to achieve a diversity of synaptic efficacy and dynamics.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:bkunes@ist.ac.at
SUMMARY:David A. DiGregorio: Synaptic basis of neural circuit computations
URL:https://talks-calendar.ista.ac.at/events/253
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