BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20170326T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
END:DAYLIGHT
BEGIN:STANDARD
DTSTART:20161030T020000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10
TZNAME:CET
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20260428T110326Z
UID:585d0b7db39e7687526770@ist.ac.at
DTSTART:20170213T094500
DTEND:20170213T104500
DESCRIPTION:Speaker: Takashi Hiiragi\nAbstract: A defining feature of livin
 g systems is the capacity to break symmetry and generate well-defined form
 s and patterns through self-organisation. Our group aims to understand the
  principle of multi-cellular self-organisation using a well-suited model s
 ystem: early mouse embryos. Mammalian eggs lack polarity and thus symmetry
  is broken during early embryogenesis. This symmetry breaking results in t
 he formation of a blastocyst consisting of two major cell types\, the inne
 r cell mass and the trophectoderm\, each distinct in its position and gene
  expression. Our recent studies unexpectedly revealed that morphogenesis a
 nd gene expression are highly dynamic and stochastically variable during t
 his process. Determining which signal breaks the symmetry and how the blas
 tocyst establishes a reproducible shape and pattern despite the preceding 
 variability remains fundamental open questions in mammalian development. W
 e have recently developed a unique set of experimental frameworks that int
 egrate biology and physics. With this we aim to understand how molecular\,
  cellular and physical signals are dynamically coupled across the scales f
 or self-organisation during early mammalian development.
LOCATION:Seminar room Big Ground floor / Office Bldg West (I21.EG.101)\, IS
 TA
ORGANIZER:pdelreal@ist.ac.at
SUMMARY:Takashi Hiiragi: Symmetry breaking and self-organisation in mouse d
 evelopment
URL:https://talks-calendar.ista.ac.at/events/249
END:VEVENT
END:VCALENDAR