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DTSTART:20200329T030000
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DTSTART:20191027T020000
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DTSTAMP:20260403T220527Z
UID:5e16e14f1c1fb362219907@ist.ac.at
DTSTART:20200117T140000
DTEND:20200117T150000
DESCRIPTION:Speaker: Sebastian Bednarek\nhosted by Jiri Friml\nAbstract: Pl
 ant morphogenesis is highly dependent upon vesicular trafficking for the  
 localization and function of proteins\, lipids and polysaccharides involve
 d in various processes including cytokinesis\, cell wall biosynthesis\, ho
 rmone signaling\, nutrient uptake and pathogen defense. In all eukaryotes\
 , exocytosis\, the process by which vesicles transport protein and other c
 argo from the Golgi apparatus to the plasma membrane\, requires conserved 
 members of the Sec4/Rab8/RabE1 GTPase family. However\, the Rab guanine nu
 cleotide exchange factors (GEFs)\, responsible for the regulation of exocy
 tosis in plants and the Opisthokonta (yeast and metazoans) are evolutionar
 ily distinct\, having likely arisen independently due to the increased com
 plexity of membrane trafficking pathways necessary for cytokinesis and pol
 arized cell expansion in these organisms relative to their common eukaryot
 ic ancestors. Understanding the functions of Rab GEFs involved in exocytos
 is and how they are regulated is therefore of central importance. Our rece
 nt work has identified a multisubunit complex\, the SCD complex\, which is
  required for the activation of plant RabE1 GTPases and exocytic vesicle t
 rafficking to the cell plate and plasma membrane in dividing and non-divid
 ing cells\, respectively. Biochemical\, genetic and imaging studies aimed 
 at understanding the network of interactions between SCD subunits that gov
 ern complex assembly\, GEF activity\, and interaction with downstream effe
 ctors required for exocytic trafficking during cytokinesis and cell expans
 ion will be presented.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:ngnyliuk@ist.ac.at
SUMMARY:Sebastian Bednarek: Evolutionarily-Conserved and Plant-Specific Tra
 fficking Machinery Required for Cytokinesis and Cell Expansion
URL:https://talks-calendar.ista.ac.at/events/2488
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