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DTSTART:20200329T030000
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DTSTART:20191027T020000
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BEGIN:VEVENT
DTSTAMP:20260405T004702Z
UID:5df8b16aa1543495401364@ist.ac.at
DTSTART:20200127T120000
DTEND:20200127T130000
DESCRIPTION:Speaker: Jerome Epsztein\nhosted by Peter Jonas\nAbstract: In a
 ny given environment\, a specific ensemble of cells in the hippocampus\, c
 alled place cells\, will be active (each one coding a specific location\, 
 their place field) among a larger population of silent neurons. This ensem
 ble participates in the formation of a cognitive map\, a mental representa
 tion of that environment which will be stored in long-term memory\, allowi
 ng flexible spatial navigation. The mechanisms behind place cells activati
 on are still poorly understood. At the network level\, place cells integra
 te information from external sensory cues as well as self-motion cues. In 
 the first part of the talk I will describe the use of virtual reality in c
 ombination with large-scale extracellular recordings to assess the role of
  local visual cues in place cells activation. At the cellular level\, the 
 mechanisms behind place cell activation are difficult to study with extrac
 ellular recordings\, which only capture the spiking output of neurons and 
 not their synaptic inputs or intrinsic cellular properties. In the second 
 part of talk I will describe recently developed techniques to perform intr
 acellular recording of hippocampal pyramidal cells in navigating animals. 
 I will illustrate how these techniques can been used to gain insights into
  the cellular mechanisms of place cell activation in new and familiar envi
 ronments.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:ekrallib@ist.ac.at
SUMMARY:Jerome Epsztein: Sensory and cellular determinants of hippocampal p
 lace cells' activation in mice navigating familiar virtual environments
URL:https://talks-calendar.ista.ac.at/events/2467
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