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DTSTART:20190331T030000
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DTSTART:20191027T020000
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DTSTAMP:20260404T064808Z
UID:5d35b0e0a9eb8802473625@ist.ac.at
DTSTART:20190731T150000
DTEND:20190731T160000
DESCRIPTION:Speaker: Ole Paulsen\nhosted by Jozsef Csicsvari\nAbstract: Spi
 ke timing-dependent synaptic plasticity is often assumed to underlie behav
 ioural learning and memory\, but the difference in timescales between the 
 rules of synaptic plasticity (tens of milliseconds) and behaviour (seconds
 \, minutes or longer) has proven difficult to explain. Neuromodulation may
  serve as a mechanism to bridge these different time scales. Synaptic plas
 ticity is known to be under neuromodulatory control\, and this presentatio
 n will discuss how neuromodulation can influence the rules of synaptic pla
 sticity\, not only when acting concurrently with spiking activity\, but al
 so when acting prior to or following the spike patterns that induced plast
 icity. Such experimental findings at synaptic level could have implication
 s for our understanding of how context influences learning and how learnin
 g may be influenced by the outcome of actions. I will describe a set of ex
 periments to investigate the neuromodulatory control of hippocampal spike 
 timing-dependent synaptic plasticity\, introduce a simple computational mo
 del using these plasticity rules to make predictions about the behavioural
  consequences for hippocampus-dependent learning\, and present some data t
 esting these predictions in behaving animals.
LOCATION:Mondi Seminar Room 3\, Central Building\, ISTA
ORGANIZER:rsix@ist.ac.at
SUMMARY:Ole Paulsen: Neuromodulation of plasticity - from synapse to behavi
 our
URL:https://talks-calendar.ista.ac.at/events/2041
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