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DTSTART:20190331T030000
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DTSTAMP:20260405T162359Z
UID:5c1b8b019e964834727124@ist.ac.at
DTSTART:20190327T150000
DTEND:20190327T160000
DESCRIPTION:Speaker: Benjamin L. de Bivort\nhosted by Maximilian Jösch\nAb
 stract: Individuals animals vary in their behaviors even when their geneti
 cs and environment are held constant. The mechanisms underlying this varia
 tion is still largely uncharacterized\, though we have made some progress 
 in understanding genetic and circuit variants that lead a population of an
 imals to exhibit high or low variability in behavior. These are key insigh
 ts\, but fall short of predicting the specific behavioral biases of indivi
 dual animals. We term the causal biological features that determine indivi
 dual behavioral biases "loci of individuality\," and we have begun to sear
 ch for them in the circuits that mediate sensory-evoked and spontaneous be
 haviors. We have found neural circuit elements\, whose morphological prope
 rties predict behavioral biases. Specifically\, the volume of axonal outpu
 t arbors of central complex neurons that project to the Lateral Accessory 
 Lobe correlates with changes in locomotor behavior in specific sensory con
 texts. We hypothesize that individual wiring variation in these neurons ha
 s a large effect on behavior because they lie at a bottleneck in the senso
 rimotor circuit\, where stochastic fluctuations have an outsized effect on
  circuit outputs. Thus\, we have found that individual variation in the st
 ructure of small numbers of neurons\, in topologically critical circuit po
 sitions\, predict individual behavioral biases in a sensory-context specif
 ic fashion.
LOCATION:Seminar Room\, Lab Building East\, ISTA
ORGANIZER:rsix@ist.ac.at
SUMMARY:Benjamin L. de Bivort: The neural circuit basis of behavioral indiv
 iduality
URL:https://talks-calendar.ista.ac.at/events/1876
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