BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:Europe/Vienna
BEGIN:DAYLIGHT
DTSTART:20180325T030000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=3
TZNAME:CEST
END:DAYLIGHT
BEGIN:STANDARD
DTSTART:20181028T020000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
RRULE:FREQ=YEARLY;BYDAY=-1SU;BYMONTH=10
TZNAME:CET
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20260405T161912Z
UID:5bb31745e05a6401687324@ist.ac.at
DTSTART:20181016T130000
DTEND:20181016T140000
DESCRIPTION:Speaker: Gerhard Schütz\nhosted by Johann Georg Danzl\nAbstrac
 t: Quantification is the heart of every scientific discipline\, as it prov
 ides a solid basis to mathematical models\, which are required for underst
 anding complicated systems. Since a few ten years\, researchers have start
 ed to model also cell biological processes mathematically\, yielding predi
 ctions that are testable by experiments. In many cases\, however\, the out
 come was rather disappointing: many models  although sometimes generating 
 the correct output  did not assume the correct molecular mechanism\, there
 by leading to increased confusion instead of clarifications. Part of the p
 roblem are limitations in current measurement technologies\; ideally\, we 
 would like to directly observe and quantify molecular processes in the nat
 ural cellular context. In my talk I will showcase by a few examples\, how 
 we can determine molecular parameters like protein association\, its kinet
 ics\, and its dependence on the cellular environment directly in the livin
 g cell using single molecule techniques. I will highlight parameters that 
 have been largely overlooked\, such as forces acting on biomolecules. Fina
 lly\, I will also show some pitfalls that may occur on our way to quantita
 tive results.
LOCATION:Mondi Seminar Room 3\, Central Building\, ISTA
ORGANIZER:rsix@ist.ac.at
SUMMARY:Gerhard Schütz: Quantifying in quantitative cell biology: how\, wh
 at\, and why?
URL:https://talks-calendar.ista.ac.at/events/1471
END:VEVENT
END:VCALENDAR