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DTSTART:20180325T030000
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DTSTART:20181028T020000
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DTSTAMP:20260406T000504Z
UID:5b3f45e3da306974138492@ist.ac.at
DTSTART:20180720T093000
DTEND:20180720T104500
DESCRIPTION:Speaker: Dimitry Tegunov\nhosted by Carrie Bernecky\nAbstract: 
 The acquisition of cryo-electron microscopy (cryo-EM) data from biological
  specimens is currently largely uncoupled from subsequent data evaluation\
 , correction and processing. Therefore\, the acquisition strategy is diffi
 cult to optimize during data collection\, often leading to suboptimal micr
 oscope usage and disappointing results. Here I will discuss Warp\, a softw
 are for real-time evaluation\, correction\, and processing of cryo-EM data
  during their acquisition. Warp evaluates and monitors key parameters for 
 each recorded micrograph or tomographic tilt series in real time. Warp als
 o rapidly corrects micrographs for global and local motion\, and estimates
  the local defocus with the use of novel algorithms. The software further 
 includes a deep learning-based particle picking algorithm that rivals huma
 n accuracy to make the pre-processing pipeline truly automated. The output
  from Warp can be directly fed into established tools for particle classif
 ication and 3D image reconstruction. Warp is easy to install\, computation
 ally inexpensive\, and has an intuitive and streamlined user interface.
LOCATION:I22 Lakeside View (I22.01)\, ISTA
ORGANIZER:rsix@ist.ac.at
SUMMARY:Dimitry Tegunov: Real-time cryo-EM data pre-processing with Warp
URL:https://talks-calendar.ista.ac.at/events/1318
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