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DTSTART:20180325T030000
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DTSTAMP:20260404T093807Z
UID:5a5f2922e2976021603747@ist.ac.at
DTSTART:20180503T140000
DTEND:20180503T150000
DESCRIPTION:Speaker: Michael Do\nhosted by Maximilian Jösch\nAbstract: Ear
 th's rotation causes the intensity of environmental illumination to change
  over many orders of magnitude\, driving variations in critical parameters
  such as temperature and visibility. Accordingly\, intensity is tracked fo
 r functions that include regulation of the circadian clock\, arousal state
 \, and hormone levels. What is the neural representation of light intensit
 y\, and how does it cover the necessary range? Furthermore\, while tempora
 l resolution confers dynamism to visual perception\, temporal integration 
 provides a smoothed representation of overall illumination that is suitabl
 e for physiological regulation. How does the visual system resolve millise
 cond events while also integrating across many minutes and hours? The answ
 ers to these questions involve a division of labor among cell types\, begi
 nning with the photoreceptors. In mammals\, these are the rods\, cones\, a
 nd more recently discovered ipRGCs (intrinsically photosensitive retinal g
 anglion cells). IpRGCs are unusual in sensing light directly as well as co
 mmunicating long distances using electrical spikes. They are necessary for
  regulating diverse aspects of physiology and behavioracross broad ranges 
 of light intensity and over extended time scales. I will discuss how these
  cells are specialized for their role\, including unique characteristics o
 f the opsin that they use to capture light\, an interaction between photot
 ransduction and spike generation\, and functional heterogeneity among indi
 viduals of common morphology. Broadly speaking\, the aim is to explore how
  the biophysical properties of a cell type are matched to particular needs
  of the organism.
LOCATION:Mondi Seminar Room 2\, Central Building\, ISTA
ORGANIZER:rsix@ist.ac.at
SUMMARY:Michael Do: Sensing Light across Breadths of Intensity and Time
URL:https://talks-calendar.ista.ac.at/events/1222
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