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DTSTART:20180325T030000
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DTSTAMP:20260405T191654Z
UID:5aba4b43bc272708366283@ist.ac.at
DTSTART:20180418T110000
DTEND:20180418T120000
DESCRIPTION:Speaker: Envel Kerdaffrec\nhosted by Fyodor Kondrashov\nAbstrac
 t: Chromosomal inversions are structural rearrangements that suppress reco
 mbination and allow alleles to be co-inherited. This feature\, along with 
 the fact that inversions form parallel clines on multiple continents and h
 ave large effects on adaptive traits\, suggests that they play major roles
  in evolutionary processes\, including local adaptation. However\, despite
  many research efforts\, little is known about the selective pressures act
 ing on inversions\, and identifying the genic targets of clinal selection 
 they might carry remains a considerable challenge. My EMBO LTF fellowship 
 proposal addresses some of these long-standing questions in Drosophila mel
 anogaster\, by focusing on the previously established link between body si
 ze\, a major life history trait\, and a cosmopolitan clinal inversion\, In
 (3R)Payne. Briefly\, this project will consist in (i) identifying body-siz
 e variants potentially under selection within the inversion\, (ii) measuri
 ng the extent to which the inversion affects body size on multiple contine
 nts and (iii) establishing causality between putative targets of selection
  and body size variation. I will also present my PhD work on the genetic a
 rchitecture of seed dormancy\, a clinally varying life history trait that 
 controls the timing of seed germination and is important for local adaptat
 ion in many plant species. In a nutshell\, we found that more than half of
  the dormancy variation observed in Swedish Arabidopsis thaliana is due to
  multiple alleles at a single locus\, the previously identified dormancy g
 ene DOG1. In addition\, field experiments showed that these alleles impact
  seedling survival by affecting the timing of seed germination in nature\,
  resulting in a large fitness differential. Thus\, dormancy appears to be 
 regulated by a single\, multi-allelic\, large effect locus\, and this work
  demonstrates that adaptive traits can have a relatively simple architectu
 re and can sometimes be dissected genetically.
LOCATION:Mondi Seminar Room 1\, Central Building\, ISTA
ORGANIZER:amally@ist.ac.at
SUMMARY:Envel Kerdaffrec: The genetic basis of clinally varying life histor
 y traits in Drosophila melanogaster and Arabidopsis thaliana
URL:https://talks-calendar.ista.ac.at/events/1208
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