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DTSTART:20180325T030000
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DTSTART:20171029T020000
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DTSTAMP:20260424T140851Z
UID:5a61ec4ce9e4d468218473@ist.ac.at
DTSTART:20180313T100000
DTEND:20180313T110000
DESCRIPTION:Speaker: Oana Carja\nhosted by Fyodor Kondrashov\nAbstract: Mol
 ecular processes are fundamentally stochastic.  Randomness is the rule in 
 transcription\, translation\, cell-to-cell variation in protein levels\, a
 nd heterogeneity in interactions. One common assumption is that such pheno
 typic variation is simply noise\, and scientists often appeal to the stati
 stics of large numbers when developing deterministic theories\, ignoring a
 ny potentially adaptive role of epigenetic stochasticity. Yet evidence is 
 accumulating that epigenetic variance constitutes an evolutionary driving 
 force across diverse biological processes\, including the persistence of p
 athogens under drug pressure or the development of cancerous neoplasms. Al
 l these systems are fundamentally characterized by high levels of environm
 ental change and uncertainty: either persistent\, global\, temporal fluctu
 ations in selection pressure\, or local\, micro-environmental and spatiall
 y-defined selective forces. In this talk\, I will explore (epi)genetic str
 ategies for fluctuating selection and the fundamental differences between 
 local triggers and global spread in shaping molecular responses to environ
 mental stochasticity.
LOCATION:Big Seminar room Ground floor / Office Bldg West (I21.EG.101)\, IS
 TA
ORGANIZER:pdelreal@ist.ac.at
SUMMARY:Oana Carja: Evolving strategies for life in an uncertain world
URL:https://talks-calendar.ista.ac.at/events/1134
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